Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ECE1 | P42892 | 1/20 | 0.64 |
| ▸ | ACE | P12821 | 1/20 | 0.60 |
| ▸ | MMP2 | P08253 | 1/20 | 0.59 |
| ▸ | MMP9 | P14780 | 1/20 | 0.59 |
| ▸ | MMP8 | P22894 | 1/20 | 0.59 |
| ▸ | MME | P08473 | 1/20 | 0.58 |
| ▸ | LTA4H | P09960 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6170248 | 0.87 | ECE1 (0.62) | ECE1ACE | |
| SCHEMBL6169075 | 0.86 | ECE1 (0.77) | ECE1ACEMMELTA4H | |
| SCHEMBL6169067 | 0.86 | ECE1 (0.77) | ECE1ACEMMELTA4H | |
| SCHEMBL6169688 | 0.86 | ECE1 (0.77) | ECE1ACEMMELTA4H | |
| SCHEMBL6169693 | 0.86 | ECE1 (0.77) | ECE1ACEMMELTA4H | |
| SCHEMBL6171226 | 0.85 | ECE1 (0.73) | ECE1ACEMMELTA4H | |
| SCHEMBL6170852 | 0.85 | ECE1 (0.73) | ECE1ACEMMELTA4H | |
| SCHEMBL6171492 | 0.85 | ECE1 (0.73) | ECE1ACEMMELTA4H | |
| SCHEMBL6162600 | 0.85 | MME (0.66) | ACEMME | |
| SCHEMBL8693644 | 0.84 | MME (0.58) | ACEMME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0419327-B1 | Amino acid derivatives, method for their preparation and their therapeutic application | BIOPROJET SOC CIV (FR) | 1994-07-27 | — | — | EP | claimed |
| US-5599951-A | ENZYME INHIBITORS | SOCIETE CIVILE BIOPROJET (FR) | 1997-02-04 | — | — | US | disclosed |