Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 7/20 | 0.77 |
| ▸ | ACE | P12821 | 3/20 | 0.77 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.77 |
| ▸ | HPGD | P15428 | 1/20 | 0.77 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.77 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.77 |
| ▸ | MEN1 | O00255 | 1/20 | 0.77 |
| ▸ | MAPT | P10636 | 1/20 | 0.77 |
| ▸ | ECE1 | P42892 | 1/20 | 0.77 |
| ▸ | BLM | P54132 | 1/20 | 0.77 |
| ▸ | NPEPPS | P55786 | 1/20 | 0.77 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.77 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.51 |
| ▸ | PPARG | P37231 | 1/20 | 0.51 |
| ▸ | PPARA | Q07869 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Thiorphan SCHEMBL401174 | 0.87 | MME (1.00) | MMEACEALDH1A1HPGDMAPK1 | |
| (S)-Thiorphan SCHEMBL49662 | 0.87 | MME (1.00) | MMEACEALDH1A1HPGDMAPK1 | |
| (R)-Thiorphan SCHEMBL7312756 | 0.87 | MME (1.00) | MMEACEALDH1A1HPGDMAPK1 | |
| SCHEMBL8861607 | 0.85 | MME (0.70) | MMEACEALDH1A1HPGDMAPK1 | |
| SCHEMBL8861570 | 0.85 | MME (0.70) | MMEACEALDH1A1HPGDMAPK1 | |
| SCHEMBL8861649 | 0.85 | MME (0.83) | MMEACEALDH1A1HPGDMAPK1 | |
| SCHEMBL8861586 | 0.83 | MME (0.67) | MMEACEALDH1A1HPGDMAPK1 | |
| Thiorphan SCHEMBL399227 | 0.80 | MME (0.84) | MMEACEALDH1A1HPGDMAPK1 | |
| Thiorphan SCHEMBL10038977 | 0.80 | MME (0.78) | MMEACEALDH1A1HPGDMAPK1 | |
| SCHEMBL8861563 | 0.80 | MME (0.78) | MMEACEECE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0419327-B1 | Amino acid derivatives, method for their preparation and their therapeutic application | BIOPROJET SOC CIV (FR) | 1994-07-27 | — | — | EP | claimed |
| US-5599951-A | ENZYME INHIBITORS | SOCIETE CIVILE BIOPROJET (FR) | 1997-02-04 | — | — | US | disclosed |