SCHEMBL8862020

SCHEMBL8862020

COC(=O)c1ccc(CSCc2ccc(OCCCCCCCCc3ccc(OC)cc3)c(/C(C)=C\C(=O)O)n2)cc1

nearest known ligand 0.63

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
LTB4R Q15722 20/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8862040 0.91 LTB4R (0.66) LTB4R
SCHEMBL8862010 0.82 LTB4R (0.72) LTB4R
SCHEMBL8065585 0.77 LTB4R (1.00) LTB4R
SCHEMBL13696782 0.77 LTB4R (1.00) LTB4R
SCHEMBL8065588 0.76 LTB4R (0.98) LTB4R
SCHEMBL8734195 0.74 LTB4R (0.85) LTB4R
SCHEMBL8862110 0.74 LTB4R (0.75) LTB4R
SCHEMBL8078498 0.74 LTB4R (0.84) LTB4R
SCHEMBL8862059 0.74 LTB4R (0.82) LTB4R
SCHEMBL9114067 0.73 LTB4R (0.79) LTB4R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5656636-A TREATING PSORIASIS SMITHKLINE BEECHAM CORPORATION (US) 1997-08-12 US disclosed
US-5633258-A Pyridine compounds for treating leukotriene-related diseases SMITHKLINE BEECHAM CORPORATION (US) 1997-05-27 US disclosed
US-5631262-A Pyridine compounds for treating leukotriene-related diseases SMITHKLINE BEECHAM CORPORATION (US) 1997-05-20 US disclosed