SCHEMBL8862136

SCHEMBL8862136

CCCCCCCCCCCCOc1ccc(CSc2ccccc2C(=O)OC)nc1C=CCC(=O)O

nearest known ligand 0.48

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
LTB4R Q15722 18/20 0.48
KMT2A Q03164 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8882258 0.84 LTB4R (0.50) LTB4R
SCHEMBL8862121 0.83 LTB4R (0.57) LTB4R
SCHEMBL27447111 0.79 LTB4R (0.45) LTB4R
SCHEMBL8862049 0.78 LTB4R (0.53) LTB4R
SCHEMBL8862053 0.78 LTB4R (0.53) LTB4R
SCHEMBL8862079 0.78 LTB4R (0.41) LTB4RKMT2A
SCHEMBL27447110 0.77 LTB4R (0.52) LTB4R
SCHEMBL8862132 0.76 LTB4R (0.70) LTB4R
SCHEMBL27452197 0.76 LTB4R (0.53) LTB4R
SCHEMBL27361794 0.76 LTB4R (0.70) LTB4R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5656636-A TREATING PSORIASIS SMITHKLINE BEECHAM CORPORATION (US) 1997-08-12 US disclosed
US-5633258-A Pyridine compounds for treating leukotriene-related diseases SMITHKLINE BEECHAM CORPORATION (US) 1997-05-27 US disclosed
US-5631262-A Pyridine compounds for treating leukotriene-related diseases SMITHKLINE BEECHAM CORPORATION (US) 1997-05-20 US disclosed