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SCHEMBL8863155

SCHEMBL8863155

[CH2]C1CN(c2ccc(N3CCN(C=O)CC3)c(F)c2)C(=O)O1

nearest known ligand 0.47

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ MAOB P27338 12/20 0.47
▸ MAOA P21397 4/20 0.47
▸ LMNA P02545 1/20 0.47
▸ PTGS1 P23219 1/20 0.47
▸ CALML3 P27482 1/20 0.47
▸ SDHA P31040 1/20 0.47
▸ F10 P00742 6/20 0.43
▸ KCNH2 Q12809 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28109804 0.87 LMNA (0.52) MAOBMAOALMNAPTGS1CALML3
SCHEMBL12006681 0.85 MAOB (0.62) MAOBMAOALMNAPTGS1CALML3
SCHEMBL12478379 0.85 MAOB (0.62) MAOBMAOALMNAPTGS1CALML3
SCHEMBL17026087 0.85 MAOB (0.62) MAOBMAOALMNAPTGS1CALML3
SCHEMBL17975540 0.82 MAOB (0.49) MAOBMAOALMNAPTGS1CALML3
SCHEMBL18396815 0.82 MAOB (0.56) MAOBMAOALMNAPTGS1CALML3
SCHEMBL18396798 0.80 MAOB (0.59) MAOBMAOALMNAPTGS1CALML3
SCHEMBL8862909 0.79 MAOB (0.51) MAOBMAOALMNAPTGS1CALML3
SCHEMBL7529735 0.79 MAOB (0.66) MAOBMAOALMNAPTGS1CALML3
SCHEMBL7529741 0.79 MAOB (0.66) MAOBMAOALMNAPTGS1CALML3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5700799-A MICROBIOCIDES FOR TREATING HUMAN OR ANIMAL DISEASES PHARMACIA & UPJOHN COMPANY (US) 1997-12-23 — — US disclosed