Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.44 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
| ▸ | MME | P08473 | 2/20 | 0.38 |
| ▸ | ACE | P12821 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7345149 | 0.73 | MME (0.51) | CA12CA9MMEACEALDH1A1 | |
| SCHEMBL7351895 | 0.69 | ACE (0.50) | CA12CA9MMEACEALDH1A1 | |
| SCHEMBL8802287 | 0.69 | ACE (0.50) | CA12CA9MMEACEALDH1A1 | |
| SCHEMBL28409736 | 0.66 | CASP3 (0.38) | CA12CA9ALDH1A1L3MBTL1SMN1; SMN2 | |
| SCHEMBL11114717 | 0.65 | CA12 (0.53) | CA12CA9ACECA2ALDH1A1 | |
| SCHEMBL522649 | 0.63 | CA12 (1.00) | CA12CA9ALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL29744481 | 0.63 | CA12 (1.00) | CA12CA9ALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL7064747 | 0.62 | CA12 (0.45) | CA12CA9CA2ALDH1A1L3MBTL1 | |
| SCHEMBL7064754 | 0.62 | CA12 (0.45) | CA12CA9CA2ALDH1A1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL7085111 | 0.62 | CA12 (0.96) | CA12CA9ALDH1A1SMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5654294-A | CARDIOVASCULAR DISORDERS | BRISTOL-MYERS SQUIBB (US) | 1997-08-05 | — | — | US | disclosed |