Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.39 |
| ▸ | SNCA | P37840 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | THRB | P10828 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8680344 | 0.74 | MAPT (0.44) | MAPTSMN1; SMN2MAPK1ALDH1A1ALOX15 | |
| SCHEMBL8680559 | 0.73 | MAPT (0.41) | MAPTSMN1; SMN2MAPK1ALDH1A1ALOX15 | |
| SCHEMBL8678920 | 0.73 | MEN1 (0.56) | MAPTSNCASMN1; SMN2MAPK1ALDH1A1 | |
| SCHEMBL8680176 | 0.70 | KMT2A (0.48) | MAPTSNCASMN1; SMN2MAPK1ALDH1A1 | |
| SCHEMBL8680103 | 0.70 | MEN1 (0.46) | MAPTSNCASMN1; SMN2MAPK1ALDH1A1 | |
| SCHEMBL8680552 | 0.69 | SMN1; SMN2 (0.50) | MAPTSMN1; SMN2MAPK1ALDH1A1ALOX15 | |
| SCHEMBL4183155 | 0.67 | MEN1 (0.48) | MAPTSMN1; SMN2MAPK1ALDH1A1ALOX15 | |
| SCHEMBL8681134 | 0.67 | SMN1; SMN2 (0.48) | MAPTSMN1; SMN2MAPK1ALDH1A1HTT | |
| SCHEMBL8682138 | 0.67 | MEN1 (0.42) | MAPTSNCASMN1; SMN2MAPK1ALDH1A1 | |
| SCHEMBL8685259 | 0.67 | SMN1; SMN2 (0.52) | MAPTSMN1; SMN2MAPK1ALDH1A1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5593486-A | Photochromic hot melt ink compositions | XEROX CORPORATION (US) | 1997-01-14 | — | — | US | disclosed |