SCHEMBL4183155

SCHEMBL4183155

COc1cccc2c1OC1(C=C2)N(C)c2cc([N+](=O)[O-])ccc2C1(C)C

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.48
KMT2A Q03164 4/20 0.48
GFER P55789 1/20 0.48
MAPT P10636 9/20 0.41
LMNA P02545 5/20 0.41
GAA P10253 3/20 0.41
TDP1 Q9NUW8 3/20 0.41
RECQL P46063 3/20 0.41
NPSR1 Q6W5P4 2/20 0.41
ALPG P10696 1/20 0.41
TP53 P04637 1/20 0.41
ALOX15 P16050 1/20 0.41
HSD17B10 Q99714 1/20 0.41
KDM4E B2RXH2 1/20 0.38
ATM Q13315 1/20 0.38
SMN1; SMN2 Q16637 4/20 0.38
ALDH1A1 P00352 2/20 0.38
MAPK1 P28482 1/20 0.38
HPGD P15428 2/20 0.37
HTT P42858 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30480955 1.00 MEN1 (0.48) MEN1KMT2AGFERMAPTLMNA
SCHEMBL8678920 0.93 MEN1 (0.56) MEN1KMT2AGFERMAPTLMNA
SCHEMBL29532854 0.84 MAPT (0.54) MEN1KMT2AGFERMAPTLMNA
SCHEMBL6102948 0.84 MAPT (0.54) MEN1KMT2AGFERMAPTLMNA
SCHEMBL8680674 0.83 MEN1 (0.43) MEN1KMT2AGFERMAPTLMNA
SCHEMBL30612732 0.82 MAPT (0.50) MEN1KMT2AGFERMAPTLMNA
SCHEMBL29473569 0.82 MAPT (0.50) MEN1KMT2AGFERMAPTLMNA
SCHEMBL30612721 0.82 KMT2A (0.57) MEN1KMT2AGFERMAPTLMNA
SCHEMBL13326515 0.82 MAPT (0.50) MEN1KMT2AGFERMAPTLMNA
SCHEMBL11788015 0.82 KMT2A (0.57) MEN1KMT2AGFERMAPTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12427798-B2 Heat-sensitive recording composition NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2025-09-30 US disclosed
US-20250001788-A1 HEAT-SENSITIVE RECORDING COMPOSITION NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2025-01-02 US disclosed
EP-4442467-A1 THERMAL RECORDING COMPOSITION Nippon Kayaku Kabushiki Kaisha (JP) 2024-10-09 EP disclosed
EP-4442468-A1 HEAT-SENSITIVE RECORDING COMPOSITION Nippon Kayaku Kabushiki Kaisha (JP) 2024-10-09 EP disclosed
US-20240326501-A1 HEAT-SENSITIVE RECORDING COMPOSITION NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2024-10-03 US disclosed
EP-3395583-B1 HEAT-SENSITIVE RECORDING MATERIAL NIPPON KAYAKU KK (JP) 2024-03-27 EP disclosed
WO-2023100902-A1 HEAT-SENSITIVE RECORDING COMPOSITION 日本化薬株式会社 2023-06-08 WO disclosed
WO-2023100900-A1 THERMAL RECORDING COMPOSITION 日本化薬株式会社 2023-06-08 WO disclosed
US-10780724-B2 Heat-sensitive recording material NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2020-09-22 US disclosed
US-10343438-B2 Heat-sensitive recording material NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2019-07-09 US disclosed
US-20040043236-A1 Heat-sensitive adhesive material RICOH COMPANY, LTD. (JP) 2004-03-04 US disclosed
US-6696150-B2 THERMOPLASTIC RESIN AND SOLID PLASTICIZER; LABELS RICOH COMPANY LTD. (JP) 2004-02-24 US disclosed
EP-0913267-B1 THERMAL RECORDING MATERIAL AND NOVEL CRYSTAL OF BISPHENOL S DERIVATIVE NIPPON KAYAKU KK (JP) 2004-01-21 EP disclosed
US-20030175507-A1 Heat-sensitive adhesive material RICOH COMPANY, LTD. 2003-09-18 US disclosed
EP-1327671-A1 Heat-sensitive adhesive material Ricoh Company, Ltd. (JP) 2003-07-16 EP disclosed
US-6114282-A CRYSTALS OF 3,3'-DIALLYL-4,4'-DIHYDROXYDIPHENYL SULFONEDEVELOPER NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2000-09-05 US disclosed
EP-0812702-B1 Thermal recording material NIPPON KAYAKU KK (JP) 2000-05-24 EP disclosed
US-5928987-A SUPERIOR IN SENSITIVITY AND IMAGE DURABILITY, HAS GOOD RESISTANCE TO HEAT AND MOISTURE AND CAN BE EASILY RECYCLED NIPPON KAYAKU CO., LTD. (JP) 1999-07-27 US disclosed
EP-0913267-A1 THERMAL RECORDING MATERIAL AND NOVEL CRYSTAL OF BISPHENOL S DERIVATIVE Nippon Kayaku Kabushiki Kaisha (JP) 1999-05-06 EP disclosed
EP-0812702-A1 Thermal recording material NIPPON KAYAKU CO., LTD. (JP) 1997-12-17 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10780724-B2 Heat-sensitive recording material KCNH2, KCNH3, TRPA1 MEN1 2769/4885KMT2A 698/4885GFER 1020/4885
US-10343438-B2 Heat-sensitive recording material SCN1A, SCN3A, KCNN3 MEN1 1050/4885KMT2A 1505/4885GFER 3197/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.