SCHEMBL8864

SCHEMBL8864

O=COC12CC3CC(CC(C3)C1)C2

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 2/20 0.43
LMNA P02545 2/20 0.33
TSHR P16473 2/20 0.33
CYP19A1 P11511 2/20 0.33
SLC22A2 O15244 1/20 0.33
SLC22A1 O15245 1/20 0.33
GRIN2D O15399 1/20 0.33
GRIN3B O60391 1/20 0.33
NFKB1 P19838 1/20 0.33
STAT6 P42226 1/20 0.33
GRIN1 Q05586 1/20 0.33
GRIN2A Q12879 1/20 0.33
GRIN2B Q13224 1/20 0.33
GRIN2C Q14957 1/20 0.33
GRIN3A Q8TCU5 1/20 0.33
SLC47A1 Q96FL8 1/20 0.33
SIGMAR1 Q99720 1/20 0.33
ALDH1A1 P00352 2/20 0.33
MEN1 O00255 1/20 0.33
HTT P42858 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28347198 0.97 NPSR1 (0.41) NPSR1LMNATSHRCYP19A1SLC22A2
SCHEMBL28760555 0.97 NPSR1 (0.41) NPSR1LMNATSHRCYP19A1SLC22A2
SCHEMBL29104085 0.97 NPSR1 (0.41) NPSR1LMNATSHRCYP19A1SLC22A2
SCHEMBL28478184 0.97 NPSR1 (0.41) NPSR1LMNATSHRCYP19A1SLC22A2
SCHEMBL20699280 0.85 NPSR1 (0.35) NPSR1
SCHEMBL10131881 0.81 NPSR1 (0.31) NPSR1
SCHEMBL10297214 0.81 NPSR1 (0.31) NPSR1
SCHEMBL29308883 0.80 NPSR1 (0.36) NPSR1
SCHEMBL17755913 0.78 NPSR1 (0.32) NPSR1
SCHEMBL5672670 0.78 NPSR1 (0.41) NPSR1LMNATSHRCYP19A1SLC22A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 11897 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122080649-A High-powder-eating silicone rubber modified based on vinyl silicone oil and preparation method thereof 2026-05-26 CN claimed
CN-122011329-A High-resistance waterborne polyurethane resin as well as preparation method and application thereof 中山市明逸化工新材料有限公司 2026-05-12 CN claimed
CN-122010965-A Photochromic spiropyran derivative containing adamantyl group and preparation method and application thereof 安徽师范大学 2026-05-12 CN claimed
CN-115639302-B Method for detecting content of 1-adamantanecarboxylic acid in soil and water by gas chromatography 贵州健安德科技有限公司 2025-06-24 CN claimed
CN-120136747-A Method for preparing adamantane esterified product by utilizing microchannel reactor 苏州威迈芯材半导体有限公司 2025-06-13 CN claimed
CN-119613861-A Self-repairing material for photovoltaic cable and preparation method thereof 曾玉峰 2025-03-14 CN claimed
CN-116426039-B Magnetic metal-polyphenol network material based on beta-cyclodextrin and preparation method and application thereof 吉林大学 2025-02-07 CN claimed
EP-3702393-B1 PRODUCTION METHOD FOR LOW INCLUSION RATE POLYROTAXANE ASM INC (JP) 2025-01-15 EP claimed
CN-116135868-B Method for heteroaryl treatment of eighth main group metallocene compound 中国科学院大连化学物理研究所 2024-11-01 CN claimed
CN-118666703-A Preparation method of 1-adamantane formamide 浙江荣耀生物科技股份有限公司 2024-09-20 CN claimed
US-3993646-A Process for the ring expansion of penicillins to cephalosporin compounds FUJISAWA PHARMACEUTICAL CO., LTD. (JA) 1976-11-23 US claimed
US-3992530-A [D-2-(1,4-Cyclohexadienyl)gly]6 -des-gly10 -lrh nonapeptide amides AMERICAN HOME PRODUCTS CORPORATION (US) 1976-11-16 US claimed
US-3978063-A 1,2,3,4-Tetrahydroisoquinoline derivatives and the preparation thereof FUJISAWA PHARMACEUTICAL CO., LTD. (JA) 1976-08-31 US claimed
US-3971737-A [2-Methyl-Ala6 ]LRH AMERICAN HOME PRODUCTS CORPORATION (US) 1976-07-27 US claimed
US-3953416-A Synthetic decapeptide having the activity of the luteinizing hormone releasing hormone and method for manufacturing the same FOLKERS KARL 1976-04-27 US claimed
US-3941763-A POLYPEPTIDE AMERICAN HOME PRODUCTS CORPORATION (US) 1976-03-02 US claimed
US-3940380-A P-Glu-D-Phe-Trp-Ser-Tyr-2-Me.Ala-Leu-Arg-Pro-NH2 and intermediates AMERICAN HOME PRODUCTS CORPORATION (US) 1976-02-24 US claimed
US-3937695-A P-Glu-Trp-Ser-Tyr-D-Lys-Leu-Arg-Pro-Gly-NH2 and intermediates AMERICAN HOME PRODUCTS CORPORATION (US) 1976-02-10 US claimed
US-3933782-A (N-Acetyl)-Pro-D-Phe-Trp-Ser-Tyr-D-Ala-Leu-Arg-Pro-NHEt and intermediates AMERICAN HOME PRODUCTS CORPORATION (US) 1976-01-20 US claimed
US-3932489-A Process for t-butylating hydroxy- or thiol-substituted amino acids ELI LILLY AND COMPANY (US) 1976-01-13 US claimed