Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29159470 | 0.86 | KMT2A (0.32) | NPSR1 | |
| SCHEMBL17755915 | 0.86 | THRB (0.39) | NPSR1 | |
| SCHEMBL25738316 | 0.86 | PKM (0.42) | NPSR1 | |
| SCHEMBL4879986 | 0.86 | PKM (0.42) | NPSR1 | |
| SCHEMBL8864 | 0.85 | NPSR1 (0.43) | NPSR1 | |
| SCHEMBL28347198 | 0.83 | NPSR1 (0.41) | NPSR1 | |
| SCHEMBL28478184 | 0.83 | NPSR1 (0.41) | NPSR1 | |
| SCHEMBL29104085 | 0.83 | NPSR1 (0.41) | NPSR1 | |
| SCHEMBL28760555 | 0.83 | NPSR1 (0.41) | NPSR1 | |
| SCHEMBL14670207 | 0.81 | PKM (0.44) | NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110997612-B | Iron catalyzed cross-coupling of methanol with secondary or tertiary alcohols to produce formate esters | 伊士曼化工公司 | 2023-10-24 | — | — | CN | disclosed |
| EP-3661906-A1 | IRON-CATALYZED CROSS-COUPLING OF METHHANOL WITH SECONDARY OR TERTIARY ALCOHOLS TO PRODUCE FORMATE ESTERS | Eastman Chemical Company (US) | 2020-06-10 | — | — | EP | disclosed |
| CN-110997612-A | Iron-catalyzed cross-coupling of methanol with secondary or tertiary alcohols to produce formates | 伊士曼化工公司 | 2020-04-10 | — | — | CN | disclosed |
| US-10435349-B2 | Iron-catalyzed cross-coupling of methanol with secondary or tertiary alcohols to produce formate esters | EASTMAN CHEMICAL COMPANY (US) | 2019-10-08 | — | — | US | disclosed |
| WO-2019027962-A1 | IRON-CATALYZED CROSS-COUPLING OF METHHANOL WITH SECONDARY OR TERTIARY ALCOHOLS TO PRODUCE FORMATE ESTERS | EASTMAN CHEMICAL COMPANY (US) | 2019-02-07 | — | — | WO | disclosed |
| US-20190039992-A1 | IRON-CATALYZED CROSS-COUPLING OF METHANOL WITH SECONDARY OR TERTIARY ALCOHOLS TO PRODUCE FORMATE ESTERS | EASTMAN CHEMICAL COMPANY (US) | 2019-02-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10435349-B2 | Iron-catalyzed cross-coupling of methanol with secondary or tertiary alcohols to produce formate esters | FTH1, FOS, ADH1A | NPSR1 3126/4885 |
| US-20190039992-A1 | IRON-CATALYZED CROSS-COUPLING OF METHANOL WITH SECONDARY OR TERTIARY ALCOHOLS TO PRODUCE FORMATE ESTERS | FTH1, FOS, ADH1A | NPSR1 3126/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.