Oxalic Acid

Oxalic Acid

SCHEMBL8864582

Brc1ccc2c(c1)CCC(CNCCCNC1=NCCCN1)O2.O=C(O)C(=O)O.O=C(O)C(=O)O

nearest known ligand 0.73

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

OPRM1SLC6A4

The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
HTR1A P08908 16/20 0.73
HTR1D P28221 16/20 0.73

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Oxalic Acid SCHEMBL8864589 1.00 HTR1A (0.73) HTR1AHTR1D
Alniditan SCHEMBL29412188 0.82 HTR1A (1.00) HTR1AHTR1D
Alniditan SCHEMBL717887 0.82 HTR1A (1.00) HTR1AHTR1D
Alniditan SCHEMBL717888 0.82 HTR1A (1.00) HTR1AHTR1D
Oxalic Acid SCHEMBL8864011 0.82 HTR1A (0.68) HTR1AHTR1D
Oxalic Acid SCHEMBL8864004 0.82 HTR1A (0.68) HTR1AHTR1D
Alniditan SCHEMBL7918202 0.82 HTR1A (0.98) HTR1AHTR1D
Alniditan SCHEMBL7918206 0.82 HTR1A (0.98) HTR1AHTR1D
Alniditan SCHEMBL8864171 0.81 HTR1A (0.96) HTR1AHTR1D
Alniditan SCHEMBL8864173 0.81 HTR1A (0.96) HTR1AHTR1D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5703115-A VASOCONSTRICTORS JANSSEN PHARMACEUTICA, N.V. (BE) 1997-12-30 US disclosed
US-5688952-A VASOCONSTRICTOR INTERMEDIATES JANSSEN PHARMACEUTICA, N.V. (BE) 1997-11-18 US disclosed
US-5624952-A VASOCONSTRICTORS JANSSEN PHARMACEUTICA N.V. (BE) 1997-04-29 US disclosed
US-5607949-A VASOCONTRICTORS, TREATING MIGRAIN JANSSEN PHARMACEUTICA N.V. (BE) 1997-03-04 US disclosed
US-5541180-A HEADACHE THERAPY JANSSEN PHARMACEUTICA N.V. (BE) 1996-07-30 US disclosed