Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | APAF1 | O14727 | 1/20 | 0.55 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.55 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.49 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 3/20 | 0.46 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1787207 | 0.83 | MAPK13 (0.41) | KDM4ETSHRAPAF1HSP90AA1HSP90AB1 | |
| SCHEMBL29382447 | 0.79 | SMN1; SMN2 (0.70) | KDM4EL3MBTL1SMN1; SMN2ALDH1A1POLB | |
| SCHEMBL8865179 | 0.72 | HPGD (0.53) | SMN1; SMN2ALDH1A1POLBTDP1HPGD | |
| SCHEMBL8224982 | 0.72 | HPGD (0.74) | KDM4EL3MBTL1SMN1; SMN2ALDH1A1POLB | |
| SCHEMBL20074822 | 0.71 | SLC34A1 (0.42) | TP53MAPTMEN1GAAKMT2A | |
| SCHEMBL1785262 | 0.71 | ROCK1 (0.55) | KDM4ETSHRSMN1; SMN2ALDH1A1POLB | |
| SCHEMBL13184428 | 0.69 | SLC34A1 (0.53) | KDM4EALDH1A1POLBTHRBPKM | |
| SCHEMBL20074778 | 0.69 | SLC34A1 (0.41) | ALDH1A1BRD4 | |
| SCHEMBL31617643 | 0.69 | SLC34A1 (0.42) | KDM4EPOLBPKMHTTMEN1 | |
| SCHEMBL25208830 | 0.69 | MAPK14 (0.40) | ALDH1A1BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5667931-A | THERMAL RESISTANCE, RESOLUTION, PHOTOSENSITIVITY | KOREA KUMHO PETROCHEMICAL CO., LTD. (KR) | 1997-09-16 | — | — | US | disclosed |
| US-5624922-A | Aryl-fused and hetaryl-fused-2,4-diazepine and 2,4-diazocine antiarrhythmic agents | STERLING WINTHROP INC. (US) | 1997-04-29 | — | — | US | disclosed |
| EP-0597540-B1 | Aryl-fused and hetaryl-fused-2,4-diazocine antiarrhythmic agents | STERLING WINTHROP INC (US) | 1996-06-05 | — | — | EP | disclosed |
| US-5380721-A | Aryl-fused and hetaryl-fused-2,4-diazepine and 2,4-diazocine antiarrhythmic agents | STERLING WINTHROP INC. (US) | 1995-01-10 | — | — | US | disclosed |
| EP-0597540-A1 | Aryl-fused and hetaryl-fused-2,4-diazocine antiarrhythmic agents | STERLING WINTHROP INC. (US) | 1994-05-18 | — | — | EP | disclosed |