Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 3/20 | 0.73 |
| ▸ | MEN1 | O00255 | 2/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.67 |
| ▸ | CDC25B | P30305 | 2/20 | 0.63 |
| ▸ | ATM | Q13315 | 1/20 | 0.63 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.61 |
| ▸ | CDC25A | P30304 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.56 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | PLOD2 | O00469 | 1/20 | 0.50 |
| ▸ | PLOD3 | O60568 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 2-Benzoylbenzoic Acid SCHEMBL76332 | 0.85 | AKR1C3 (1.00) | AKR1C3CDC25BATMNR4A1CDC25A | |
| 2-Benzoylbenzoic Acid SCHEMBL30296847 | 0.85 | AKR1C3 (1.00) | AKR1C3CDC25BATMNR4A1CDC25A | |
| SCHEMBL27524893 | 0.85 | AKR1C3 (0.91) | AKR1C3CDC25BATMNR4A1CDC25A | |
| 2-Benzoylbenzoic Acid SCHEMBL1525895 | 0.83 | AKR1C3 (0.95) | AKR1C3CDC25BATMNR4A1CDC25A | |
| 2-Benzoylbenzoic Acid SCHEMBL10979285 | 0.83 | AKR1C3 (0.95) | AKR1C3CDC25BATMNR4A1CDC25A | |
| 2-Benzoylbenzoic Acid SCHEMBL9317427 | 0.83 | AKR1C3 (0.95) | AKR1C3CDC25BATMNR4A1CDC25A | |
| 2-Benzoylbenzoic Acid SCHEMBL11577549 | 0.83 | AKR1C3 (0.95) | AKR1C3CDC25BATMNR4A1CDC25A | |
| 2-Benzoylbenzoic Acid SCHEMBL3791911 | 0.83 | AKR1C3 (0.95) | AKR1C3CDC25BATMNR4A1CDC25A | |
| 2-Benzoylbenzoic Acid SCHEMBL9562236 | 0.83 | AKR1C3 (0.95) | AKR1C3CDC25BATMNR4A1CDC25A | |
| 2-Benzoylbenzoic Acid SCHEMBL7768301 | 0.83 | AKR1C3 (0.95) | AKR1C3CDC25BATMNR4A1CDC25A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9638690-B2 | Compounds and compositions for use as alkylating agent sensors and methods of use thereof | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2017-05-02 | — | — | US | disclosed |
| US-9638690-B2 | Compounds and compositions for use as alkylating agent sensors and methods of use thereof | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2017-05-02 | — | — | US | disclosed |
| US-20160131641-A1 | COMPOUNDS AND COMPOSITIONS FOR USE AS ALKYLATING AGENT SENSORS AND METHODS OF USE THEREOF | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2016-05-12 | — | — | US | disclosed |
| US-20160131641-A1 | COMPOUNDS AND COMPOSITIONS FOR USE AS ALKYLATING AGENT SENSORS AND METHODS OF USE THEREOF | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2016-05-12 | — | — | US | disclosed |
| US-5624922-A | Aryl-fused and hetaryl-fused-2,4-diazepine and 2,4-diazocine antiarrhythmic agents | STERLING WINTHROP INC. (US) | 1997-04-29 | — | — | US | disclosed |
| EP-0597540-B1 | Aryl-fused and hetaryl-fused-2,4-diazocine antiarrhythmic agents | STERLING WINTHROP INC (US) | 1996-06-05 | — | — | EP | disclosed |
| US-5380721-A | Aryl-fused and hetaryl-fused-2,4-diazepine and 2,4-diazocine antiarrhythmic agents | STERLING WINTHROP INC. (US) | 1995-01-10 | — | — | US | disclosed |
| EP-0597540-A1 | Aryl-fused and hetaryl-fused-2,4-diazocine antiarrhythmic agents | STERLING WINTHROP INC. (US) | 1994-05-18 | — | — | EP | disclosed |
| US-5268372-A | Where nitrogen in position 2 and 5 are connected by a methylene bridge | STERLING WINTHROP INC. (US) | 1993-12-07 | — | — | US | disclosed |
| US-5206231-A | 2,5-benzodiazocine antiarrhythmic agents | STERLING DRUG INC. (US) | 1993-04-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160131641-A1 | COMPOUNDS AND COMPOSITIONS FOR USE AS ALKYLATING AGENT SENSORS AND METHODS OF USE THEREOF | MGMT, MCL1, OGG1 | AKR1C3 3472/4885MEN1 341/4885KMT2A 311/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.