Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 15/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CTSS | P25774 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8728468 | 1.00 | CTSK (0.43) | CTSKCA1CA2CA7CTSS | |
| SCHEMBL738693 | 0.84 | CA1 (0.43) | CTSKCA1CA2CA7CTSS | |
| SCHEMBL166623 | 0.79 | CA1 (0.42) | CTSKCA1CA2CA7CTSS | |
| SCHEMBL7878490 | 0.75 | CTSK (0.43) | CTSKCA1CA2CA7CTSS | |
| SCHEMBL166206 | 0.74 | CA1 (0.42) | CTSKCA1CA2CA7CTSS | |
| SCHEMBL8864839 | 0.74 | CA1 (0.41) | CTSKCA1CA2CA7CTSS | |
| SCHEMBL6612741 | 0.74 | TDP1 (0.44) | CTSKCA1CA2CA7CYP2D6 | |
| SCHEMBL17019827 | 0.73 | MEN1 (0.46) | CTSKCA1CA2CA7CTSS | |
| SCHEMBL9220420 | 0.73 | MEN1 (0.46) | CTSKCA1CA2CA7CTSS | |
| SCHEMBL19628801 | 0.73 | MEN1 (0.46) | CTSKCA1CA2CA7CTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5686469-A | ANTIINFLAMMATORY AGENTS | MILES INC. (US) | 1997-11-11 | — | — | US | claimed |
| US-5686469-A | ANTIINFLAMMATORY AGENTS | MILES INC. (US) | 1997-11-11 | — | — | US | disclosed |