Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | RARA | P10276 | 1/20 | 0.33 |
| ▸ | RARB | P10826 | 1/20 | 0.33 |
| ▸ | RARG | P13631 | 1/20 | 0.33 |
| ▸ | BCL9 | O00512 | 1/20 | 0.32 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.32 |
| ▸ | ACACB | O00763 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8864961 | 0.92 | PTGDR2 (0.33) | KMT2ACYP3A4RARARARBRARG | |
| SCHEMBL8865609 | 0.91 | KMT2A (0.35) | KMT2ACYP3A4RARARARBRARG | |
| SCHEMBL8865509 | 0.87 | — | — | |
| SCHEMBL8865740 | 0.86 | CYP3A4 (0.43) | KMT2ACYP3A4RARARARBRARG | |
| SCHEMBL8865678 | 0.85 | AKR1B1 (0.31) | — | |
| SCHEMBL8865558 | 0.83 | AKR1B1 (0.30) | — | |
| SCHEMBL8865958 | 0.81 | RARA (0.51) | KMT2ACYP3A4RARARARBRARG | |
| SCHEMBL8865217 | 0.81 | CYP3A4 (0.37) | KMT2ACYP3A4RARARARBRARG | |
| SCHEMBL8864919 | 0.81 | CYP3A4 (0.38) | KMT2ACYP3A4RARARARBRARG | |
| SCHEMBL8874982 | 0.80 | CYP26A1 (0.40) | KMT2ACYP3A4RARARARBRARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5677323-A | SKIN DISORDERS, PSORIASIS | ALLERGAN (US) | 1997-10-14 | — | — | US | disclosed |