Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARA | P10276 | 4/20 | 0.43 |
| ▸ | RARB | P10826 | 4/20 | 0.43 |
| ▸ | RARG | P13631 | 4/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CYP26A1 | O43174 | 2/20 | 0.40 |
| ▸ | ACACB | O00763 | 6/20 | 0.34 |
| ▸ | HSPA9 | P38646 | 1/20 | 0.32 |
| ▸ | CRABP2 | P29373 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8865407 | 0.86 | RARA (0.33) | RARARARBRARGCYP3A4KMT2A | |
| SCHEMBL8865344 | 0.86 | RARA (0.45) | RARARARBRARGCYP3A4KMT2A | |
| SCHEMBL8864822 | 0.85 | RARA (0.33) | RARARARBRARGCYP3A4KMT2A | |
| SCHEMBL8864901 | 0.82 | RARA (0.41) | RARARARBRARGCYP3A4KMT2A | |
| SCHEMBL8865003 | 0.82 | RARA (0.30) | RARARARBRARG | |
| SCHEMBL8865444 | 0.81 | CYP3A4 (0.38) | RARARARBRARGCYP3A4KMT2A | |
| SCHEMBL8865237 | 0.80 | RARA (0.49) | RARARARBRARGCYP3A4KMT2A | |
| SCHEMBL8662237 | 0.80 | CYP3A4 (0.47) | RARARARBRARGCYP3A4KMT2A | |
| SCHEMBL8864915 | 0.79 | RARA (0.38) | RARARARBRARGCYP3A4KMT2A | |
| SCHEMBL8865070 | 0.79 | RARA (0.38) | RARARARBRARGCYP3A4KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5677323-A | SKIN DISORDERS, PSORIASIS | ALLERGAN (US) | 1997-10-14 | — | — | US | disclosed |