Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | RARA | P10276 | 1/20 | 0.30 |
| ▸ | RARB | P10826 | 1/20 | 0.30 |
| ▸ | RARG | P13631 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8865509 | 0.91 | — | — | |
| SCHEMBL8865438 | 0.89 | — | — | |
| SCHEMBL8865609 | 0.87 | KMT2A (0.35) | CYP3A4RARARARBRARGKMT2A | |
| SCHEMBL8865931 | 0.87 | PTGDR2 (0.31) | — | |
| SCHEMBL8865492 | 0.86 | AKR1B1 (0.31) | CYP3A4RARARARBRARGKMT2A | |
| SCHEMBL8865365 | 0.85 | CYP3A4 (0.39) | CYP3A4RARARARBRARGKMT2A | |
| SCHEMBL8865029 | 0.84 | — | — | |
| SCHEMBL8865822 | 0.84 | AKR1B1 (0.30) | — | |
| SCHEMBL8865783 | 0.82 | RARA (0.33) | CYP3A4RARARARBRARGKMT2A | |
| SCHEMBL8865494 | 0.81 | CYP3A4 (0.34) | CYP3A4RARARARBRARGKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5677323-A | SKIN DISORDERS, PSORIASIS | ALLERGAN (US) | 1997-10-14 | — | — | US | disclosed |