Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP1 | P11387 | 4/20 | 0.58 |
| ▸ | CYCS | P99999 | 4/20 | 0.57 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.52 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.49 |
| ▸ | PPARG | P37231 | 2/20 | 0.48 |
| ▸ | PPARA | Q07869 | 2/20 | 0.48 |
| ▸ | TERT | O14746 | 5/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25565736 | 0.83 | TERT (0.53) | TOP1CYCSABCG2ENPP2TERT | |
| SCHEMBL8865261 | 0.79 | PPARG (0.43) | TOP1CYCSABCG2ENPP2PPARG | |
| SCHEMBL10523963 | 0.78 | TOP1 (0.60) | TOP1CYCSABCG2ENPP2TERT | |
| SCHEMBL6035947 | 0.76 | TOP1 (0.46) | TOP1CYCSABCG2ENPP2TERT | |
| SCHEMBL29558419 | 0.76 | TOP1 (0.61) | TOP1CYCSABCG2ENPP2TERT | |
| SCHEMBL3794157 | 0.76 | TOP1 (0.61) | TOP1CYCSABCG2ENPP2TERT | |
| SCHEMBL25566046 | 0.75 | TERT (0.47) | TOP1CYCSABCG2ENPP2TERT | |
| SCHEMBL25565782 | 0.75 | TERT (0.45) | TOP1CYCSABCG2ENPP2TERT | |
| SCHEMBL949511 | 0.75 | TERT (0.57) | TOP1CYCSABCG2ENPP2TERT | |
| SCHEMBL29414382 | 0.75 | TERT (0.57) | TOP1CYCSABCG2ENPP2TERT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0684948-B1 | MESO-TETRAPHENYL PORPHYRIN COMPLEX COMPOUNDS, PROCESS FOR PREPARING THE SAME AND PHARMACEUTICALS CONTAINING THE SAME | DIAGNOSTIKFORSCHUNG INST (DE) | 1997-10-22 | — | — | EP | disclosed |
| US-5674467-A | USED IN NMR DIAGNOSIS, RADIODIAGNOSIS OR RADIOTHERAPY | INSTITUT FUR DIAGNOSTIKFORSCHUNG GMBH (DE) | 1997-10-07 | — | — | US | disclosed |
| WO-1994019352-A1 | MESO-TETRAPHENYL PORPHYRIN COMPLEX COMPOUNDS, PROCESS FOR PREPARING THE SAME AND PHARMACEUTICALS CONTAINING THE SAME | Institut für Diagnostikforschung GmbH an der Freien Universität Berlin (DE) | 1994-09-01 | — | — | WO | disclosed |