Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | PRNP | P04156 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | CPB1 | P15086 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2534345 | 0.79 | AKR1B1 (0.46) | ALDH1A1MAPTCYP1A2CYP2C9MEN1 | |
| SCHEMBL8419890 | 0.72 | TSHR (0.59) | TSHRALDH1A1AGTR1POLBHPGD | |
| SCHEMBL4965738 | 0.70 | TSHR (0.61) | TSHRALDH1A1AGTR1HPGDMAPT | |
| SCHEMBL29930404 | 0.70 | TSHR (0.61) | TSHRALDH1A1AGTR1HPGDMAPT | |
| SCHEMBL7115241 | 0.70 | TSHR (0.61) | TSHRALDH1A1AGTR1MAPTMEN1 | |
| SCHEMBL8754820 | 0.70 | TSHR (0.61) | TSHRALDH1A1AGTR1POLBHPGD | |
| SCHEMBL8865535 | 0.70 | MAPT (0.59) | ALDH1A1POLBHPGDMAPTHSD17B10 | |
| SCHEMBL8865552 | 0.70 | TSHR (0.43) | TSHRALDH1A1POLBHPGDMEN1 | |
| SCHEMBL4481076 | 0.69 | TSHR (0.59) | TSHRALDH1A1HPGDMAPTMEN1 | |
| SCHEMBL8851769 | 0.69 | TSHR (0.59) | TSHRALDH1A1AGTR1POLBHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5674467-A | USED IN NMR DIAGNOSIS, RADIODIAGNOSIS OR RADIOTHERAPY | INSTITUT FUR DIAGNOSTIKFORSCHUNG GMBH (DE) | 1997-10-07 | — | — | US | disclosed |