Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | CXCL8 | P10145 | 6/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.38 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.38 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.38 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.38 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.38 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.35 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.35 |
| ▸ | UGT1A9 | O60656 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8865575 | 0.79 | TSHR (0.47) | TDP1CYP1A2MAPTPTGS2PTGS1 | |
| SCHEMBL935295 | 0.77 | FABP3 (0.44) | KDM4EMAPTALDH1A1CYP2C9 | |
| SCHEMBL7827157 | 0.76 | AKR1B1 (0.67) | AKR1B1TDP1CXCL8KDM4ECYP1A2 | |
| SCHEMBL3298860 | 0.76 | PDCD1 (0.44) | ALDH1A1KMT2A | |
| SCHEMBL6688847 | 0.75 | PTGS1 (0.39) | AKR1B1KDM4ECYP1A2MAPTPTGS1 | |
| SCHEMBL498541 | 0.72 | ALDH1A1 (0.40) | TDP1KDM4EMAPTALDH1A1TTR | |
| SCHEMBL538512 | 0.71 | KMT2A (0.60) | AKR1B1TDP1PTGS2PTGER1PTGER4 | |
| SCHEMBL29410826 | 0.70 | AKR1B1 (0.76) | AKR1B1TDP1CXCL8KDM4ECYP1A2 | |
| SCHEMBL30359 | 0.70 | AKR1B1 (0.76) | AKR1B1TDP1CXCL8KDM4ECYP1A2 | |
| SCHEMBL29512995 | 0.70 | KMT2A (0.58) | AKR1B1TDP1PTGS2PTGER1PTGER4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9670217-B2 | Process for preparing chlorins and their pharmaceutical uses | UNIVERSIDADE DE COIMBRA (PT) | 2017-06-06 | — | — | US | disclosed |
| EP-2346874-B1 | PROCESS FOR PREPARING CHLORINS AND THEIR PHARMACEUTICAL USES | UNIV DE COIMBRA (PT) | 2013-12-04 | — | — | EP | disclosed |
| US-20110250143-A1 | PROCESS FOR PREPARING CHLORINS AND THEIR PHARMACEUTICAL USES | UNIVERSIDADE DE COIMBRA (PT) | 2011-10-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110250143-A1 | PROCESS FOR PREPARING CHLORINS AND THEIR PHARMACEUTICAL USES | CD68, HMBS, MKI67 | AKR1B1 2630/4885TDP1 1731/4885CXCL8 2758/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.