Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYCS | P99999 | 4/20 | 0.40 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.35 |
| ▸ | TOP1 | P11387 | 3/20 | 0.31 |
| ▸ | DHODH | Q02127 | 2/20 | 0.31 |
| ▸ | JAK2 | O60674 | 1/20 | 0.31 |
| ▸ | ICMT | O60725 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | PPARA | Q07869 | 1/20 | 0.31 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.30 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.30 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.30 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.30 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.30 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.30 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.30 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8908193 | 0.87 | CYCS (0.48) | CYCSABCG2TOP1DHODHENPP2 | |
| SCHEMBL8865603 | 0.83 | MAPT (0.37) | CYCSABCG2TOP1DHODHICMT | |
| SCHEMBL8865785 | 0.81 | MAPT (0.37) | CYCSABCG2TOP1DHODHICMT | |
| SCHEMBL8909265 | 0.81 | TOP1 (0.41) | CYCSABCG2TOP1DHODHENPP2 | |
| SCHEMBL8865213 | 0.81 | ABCG2 (0.39) | CYCSABCG2TOP1DHODHENPP2 | |
| Hydrochloric Acid SCHEMBL8865221 | 0.80 | TOP1 (0.40) | CYCSABCG2TOP1DHODHENPP2 | |
| SCHEMBL8865532 | 0.76 | PDE3B (0.34) | PPARGPPARA | |
| SCHEMBL8909297 | 0.76 | TOP1 (0.44) | CYCSABCG2TOP1DHODHENPP2 | |
| SCHEMBL8865339 | 0.75 | SYK (0.40) | CYCSABCG2TOP1 | |
| SCHEMBL8909582 | 0.74 | TOP1 (0.44) | CYCSABCG2TOP1DHODHENPP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5674467-A | USED IN NMR DIAGNOSIS, RADIODIAGNOSIS OR RADIOTHERAPY | INSTITUT FUR DIAGNOSTIKFORSCHUNG GMBH (DE) | 1997-10-07 | — | — | US | disclosed |