Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK1 | P53350 | 1/20 | 0.54 |
| ▸ | MMP3 | P08254 | 1/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | CASP1 | P29466 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | BACE1 | P56817 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | ANPEP | P15144 | 1/20 | 0.46 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.44 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.44 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8865083 | 1.00 | PLK1 (0.54) | PLK1MMP3HDAC8ALDH1A1LMNA | |
| SCHEMBL6244622 | 0.82 | CASP1 (0.57) | PLK1CASP1BACE1ANPEP | |
| SCHEMBL6244616 | 0.82 | CASP1 (0.57) | PLK1CASP1BACE1ANPEP | |
| SCHEMBL7459754 | 0.81 | CAPN1 (0.54) | PLK1MMP3HDAC8ALDH1A1LMNA | |
| SCHEMBL7459752 | 0.81 | PLK1 (0.51) | PLK1MMP3HDAC8ALDH1A1LMNA | |
| SCHEMBL8737627 | 0.80 | PLK1 (0.66) | PLK1MMP3HDAC8ALDH1A1LMNA | |
| SCHEMBL24767558 | 0.78 | MEN1 (0.67) | PLK1MMP3HDAC8ALDH1A1LMNA | |
| SCHEMBL1505526 | 0.77 | HDAC8 (0.59) | PLK1MMP3HDAC8ALDH1A1LMNA | |
| SCHEMBL8865388 | 0.77 | POLB (0.64) | ALDH1A1L3MBTL1MEN1KMT2AGAA | |
| SCHEMBL8865394 | 0.77 | POLB (0.64) | ALDH1A1L3MBTL1MEN1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5686469-A | ANTIINFLAMMATORY AGENTS | MILES INC. (US) | 1997-11-11 | — | — | US | disclosed |