Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARA | P10276 | 2/20 | 0.32 |
| ▸ | RARB | P10826 | 2/20 | 0.32 |
| ▸ | RARG | P13631 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8864880 | 0.92 | RARA (0.33) | RARARARBRARGCYP3A4KMT2A | |
| SCHEMBL8865714 | 0.91 | PTGDR2 (0.31) | — | |
| SCHEMBL8864901 | 0.87 | RARA (0.41) | RARARARBRARGCYP3A4KMT2A | |
| SCHEMBL8865433 | 0.83 | RARA (0.32) | RARARARBRARGCYP3A4KMT2A | |
| SCHEMBL8865558 | 0.82 | AKR1B1 (0.30) | — | |
| SCHEMBL8865711 | 0.81 | RARA (0.38) | RARARARBRARGCYP3A4KMT2A | |
| SCHEMBL8877092 | 0.81 | CYP3A4 (0.33) | RARARARBRARGCYP3A4KMT2A | |
| SCHEMBL8865407 | 0.80 | RARA (0.33) | RARARARBRARGCYP3A4KMT2A | |
| SCHEMBL8865668 | 0.79 | CYP3A4 (0.36) | RARARARBRARGCYP3A4KMT2A | |
| SCHEMBL8865581 | 0.79 | RARA (0.34) | RARARARBRARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5677323-A | SKIN DISORDERS, PSORIASIS | ALLERGAN (US) | 1997-10-14 | — | — | US | disclosed |