Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | HTR7 | P34969 | 2/20 | 0.55 |
| ▸ | HTR1A | P08908 | 1/20 | 0.55 |
| ▸ | DRD2 | P14416 | 1/20 | 0.55 |
| ▸ | HTR2A | P28223 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8865736 | 0.99 | MAPT (0.58) | ALDH1A1SMN1; SMN2KDM4EMAPTL3MBTL1 | |
| Hydrochloric Acid SCHEMBL8865722 | 0.99 | MAPT (0.58) | ALDH1A1SMN1; SMN2KDM4EMAPTL3MBTL1 | |
| Hydrochloric Acid SCHEMBL8865743 | 0.99 | MAPT (0.58) | ALDH1A1SMN1; SMN2KDM4EMAPTL3MBTL1 | |
| SCHEMBL8865606 | 0.89 | — | — | |
| SCHEMBL8865602 | 0.89 | — | — | |
| SCHEMBL8865588 | 0.89 | — | — | |
| Hydrochloric Acid SCHEMBL7419250 | 0.88 | — | — | |
| Hydrochloric Acid SCHEMBL7419244 | 0.88 | — | — | |
| Hydrochloric Acid SCHEMBL7419255 | 0.88 | — | — | |
| SCHEMBL7411733 | 0.85 | ALDH1A1 (0.49) | ALDH1A1SMN1; SMN2KDM4EMAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5608069-A | TREATMENT OF NERVOUS SYSTEM DISORDERS WITH GAMMA-AMINOBUTYRIC ACID | NOVO NORDISK A/S (DK) | 1997-03-04 | — | — | US | disclosed |