Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | RARA | P10276 | 1/20 | 0.49 |
| ▸ | RARB | P10826 | 1/20 | 0.49 |
| ▸ | RARG | P13631 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | ACACB | O00763 | 4/20 | 0.38 |
| ▸ | CYP26A1 | O43174 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | FDFT1 | P37268 | 1/20 | 0.35 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.34 |
| ▸ | JAK2 | O60674 | 2/20 | 0.34 |
| ▸ | JAK1 | P23458 | 2/20 | 0.34 |
| ▸ | TYK2 | P29597 | 2/20 | 0.34 |
| ▸ | JAK3 | P52333 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9209527 | 0.91 | CYP3A4 (0.47) | CYP3A4RARARARBRARGKMT2A | |
| SCHEMBL8865044 | 0.89 | CYP3A4 (0.46) | CYP3A4RARARARBRARGKMT2A | |
| SCHEMBL8876189 | 0.88 | CYP26A1 (0.43) | CYP3A4RARARARBRARGKMT2A | |
| SCHEMBL8865372 | 0.87 | CYP3A4 (0.45) | CYP3A4RARARARBRARGKMT2A | |
| SCHEMBL8865618 | 0.86 | CYP3A4 (0.39) | CYP3A4RARARARBRARGKMT2A | |
| SCHEMBL9866199 | 0.86 | CYP3A4 (0.44) | CYP3A4RARARARBRARGKMT2A | |
| SCHEMBL8626930 | 0.86 | CYP3A4 (0.65) | CYP3A4RARARARBRARGKMT2A | |
| SCHEMBL8864919 | 0.86 | CYP3A4 (0.38) | CYP3A4RARARARBRARGKMT2A | |
| SCHEMBL8865446 | 0.85 | CYP3A4 (0.43) | CYP3A4RARARARBRARGKMT2A | |
| SCHEMBL8865454 | 0.84 | CYP3A4 (0.43) | CYP3A4RARARARBRARGKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5677323-A | SKIN DISORDERS, PSORIASIS | ALLERGAN (US) | 1997-10-14 | — | — | US | disclosed |