Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | RARA | P10276 | 1/20 | 0.39 |
| ▸ | RARB | P10826 | 1/20 | 0.39 |
| ▸ | RARG | P13631 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8864919 | 0.92 | CYP3A4 (0.38) | CYP3A4RARARARBRARGKMT2A | |
| SCHEMBL8865334 | 0.91 | CYP3A4 (0.38) | CYP3A4RARARARBRARGKMT2A | |
| SCHEMBL8865303 | 0.89 | CYP3A4 (0.36) | CYP3A4RARARARBRARGKMT2A | |
| SCHEMBL8874667 | 0.89 | CYP26A1 (0.40) | CYP3A4RARARARBRARGKMT2A | |
| SCHEMBL8864973 | 0.87 | CYP3A4 (0.35) | CYP3A4RARARARBRARGKMT2A | |
| SCHEMBL8865494 | 0.86 | CYP3A4 (0.34) | CYP3A4RARARARBRARGKMT2A | |
| SCHEMBL8865751 | 0.86 | CYP3A4 (0.49) | CYP3A4RARARARBRARGKMT2A | |
| SCHEMBL8560124 | 0.86 | RARA (0.52) | CYP3A4RARARARBRARGKMT2A | |
| SCHEMBL8865498 | 0.85 | CYP3A4 (0.34) | CYP3A4RARARARBRARGKMT2A | |
| SCHEMBL8865217 | 0.83 | CYP3A4 (0.37) | CYP3A4RARARARBRARGKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5677323-A | SKIN DISORDERS, PSORIASIS | ALLERGAN (US) | 1997-10-14 | — | — | US | disclosed |