Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 14/20 | 0.62 |
| ▸ | CYP11B2 | P19099 | 14/20 | 0.62 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.46 |
| ▸ | ACE2 | Q9BYF1 | 3/20 | 0.38 |
| ▸ | ACE | P12821 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2789863 | 0.89 | CYP11B1 (0.76) | CYP11B1CYP11B2 | |
| SCHEMBL7086608 | 0.83 | CYP11B1 (0.79) | CYP11B1CYP11B2 | |
| SCHEMBL7749564 | 0.82 | CYP11B1 (0.58) | CYP11B1CYP11B2 | |
| SCHEMBL7848245 | 0.80 | CYP11B1 (0.57) | CYP11B1CYP11B2MAPK10 | |
| SCHEMBL28683880 | 0.77 | CYP11B1 (0.70) | CYP11B1CYP11B2USP2MAPK10 | |
| SCHEMBL3822953 | 0.76 | CYP11B1 (1.00) | CYP11B1CYP11B2 | |
| SCHEMBL6776094 | 0.76 | CYP11B1 (0.62) | CYP11B1CYP11B2 | |
| SCHEMBL9642312 | 0.76 | CYP11B1 (1.00) | CYP11B1CYP11B2 | |
| SCHEMBL7704743 | 0.75 | CYP11B1 (0.55) | CYP11B1CYP11B2 | |
| SCHEMBL237854 | 0.75 | CYP19A1 (0.59) | MAPK10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5652257-A | ANTICARCINOGENIC | MERCK & CO., INC. (US) | 1997-07-29 | — | — | US | disclosed |