Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 18/20 | 0.61 |
| ▸ | FNTB | P49356 | 18/20 | 0.61 |
| ▸ | MME | P08473 | 1/20 | 0.35 |
| ▸ | ACE | P12821 | 1/20 | 0.35 |
| ▸ | CPA1 | P15085 | 1/20 | 0.35 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.35 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8865554 | 0.95 | FNTA (0.55) | FNTAFNTB | |
| SCHEMBL8763043 | 0.93 | FNTA (0.67) | FNTAFNTBMMEACECPA1 | |
| SCHEMBL9060561 | 0.92 | FNTA (0.58) | FNTAFNTBPGGT1B | |
| SCHEMBL9060165 | 0.89 | FNTA (0.62) | FNTAFNTB | |
| SCHEMBL9068133 | 0.88 | FNTA (0.61) | FNTAFNTB | |
| SCHEMBL8865579 | 0.88 | FNTA (0.71) | FNTAFNTBMMEACECPA1 | |
| SCHEMBL8763050 | 0.87 | FNTA (0.59) | FNTAFNTB | |
| SCHEMBL8866072 | 0.86 | FNTA (0.69) | FNTAFNTBMMEACECPA1 | |
| SCHEMBL8762235 | 0.86 | FNTA (0.64) | FNTAFNTB | |
| SCHEMBL7516868 | 0.85 | FNTA (0.63) | FNTAFNTBPGGT1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5652257-A | ANTICARCINOGENIC | MERCK & CO., INC. (US) | 1997-07-29 | — | — | US | disclosed |
| WO-1996010034-A2 | THIOL-FREE INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | MERCK & CO., INC. (US) | 1996-04-04 | — | — | WO | disclosed |