SCHEMBL9060561

CC[C@H](C)[C@@H](CN(CC(=O)N[C@@H](CCSC)C(=O)O)Cc1cccc2ccccc12)NCCc1cncn1Cc1ccc2ccccc2c1.CC[C@H](C)[C@@H](CN(CC(=O)N[C@@H](CCSC)C(=O)OC)Cc1ccccc1)NC(=O)Cc1cncn1Cc1ccc2ccccc2c1

nearest known ligand 0.58

Predicted protein targets (top 3)

	gene	UniProt	supporting neighbours	confidence
▸	FNTA	P49354	20/20	0.58

▸	FNTB	P49356	20/20	0.58

▸	PGGT1B	P53609	1/20	0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL9060165	0.95	FNTA (0.62)	FNTAFNTB
SCHEMBL8865554	0.94	FNTA (0.55)	FNTAFNTB
SCHEMBL9068133	0.94	FNTA (0.61)	FNTAFNTB
SCHEMBL8763050	0.93	FNTA (0.59)	FNTAFNTB
SCHEMBL8866069	0.92	FNTA (0.61)	FNTAFNTBPGGT1B
SCHEMBL9058050	0.91	FNTA (0.56)	FNTAFNTB
SCHEMBL8763043	0.91	FNTA (0.67)	FNTAFNTBPGGT1B
SCHEMBL8763048	0.90	FNTA (0.51)	FNTAFNTB
SCHEMBL8865579	0.88	FNTA (0.71)	FNTAFNTBPGGT1B
SCHEMBL8763284	0.88	FNTA (0.58)	FNTAFNTB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-1996010034-A2	THIOL-FREE INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE	MERCK & CO., INC. (US)	1996-04-04	—	—	WO	claimed