Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTK | P33981 | 5/20 | 0.38 |
| ▸ | TLR2 | O60603 | 2/20 | 0.35 |
| ▸ | TLR1 | Q15399 | 2/20 | 0.35 |
| ▸ | CKS1B | P61024 | 1/20 | 0.34 |
| ▸ | SKP1 | P63208 | 1/20 | 0.34 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.34 |
| ▸ | SUCNR1 | Q9BXA5 | 3/20 | 0.34 |
| ▸ | ACACB | O00763 | 2/20 | 0.34 |
| ▸ | ACACA | Q13085 | 2/20 | 0.34 |
| ▸ | ACP1 | P24666 | 3/20 | 0.33 |
| ▸ | NAMPT | P43490 | 1/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9229601 | 0.79 | CKS1B (0.38) | TTKCKS1BSKP1SKP2ACACB | |
| SCHEMBL8866569 | 0.78 | CKS1B (0.35) | TTKCKS1BSKP1SKP2ACACB | |
| SCHEMBL8866085 | 0.74 | ACACB (0.54) | TTKCKS1BSKP1SKP2ACACB | |
| SCHEMBL8866582 | 0.73 | CKS1B (0.43) | CKS1BSKP1SKP2ACACBACACA | |
| SCHEMBL8866469 | 0.72 | ACACB (0.46) | TTKCKS1BSKP1SKP2ACACB | |
| SCHEMBL9232532 | 0.70 | ACACB (0.43) | TTKCKS1BSKP1SKP2ACACB | |
| SCHEMBL8866088 | 0.69 | ACACB (0.45) | TTKCKS1BSKP1SKP2ACACB | |
| SCHEMBL8866022 | 0.68 | SUV39H2 (0.40) | ACACBACACA | |
| SCHEMBL8866802 | 0.67 | ACACB (0.42) | CKS1BSKP1SKP2ACACBACACA | |
| SCHEMBL21004115 | 0.67 | TDP1 (0.52) | NAMPTDRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5614531-A | Adhesion receptor antagonists | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1997-03-25 | — | — | US | disclosed |