Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 8/20 | 0.42 |
| ▸ | ACACA | Q13085 | 5/20 | 0.42 |
| ▸ | CKS1B | P61024 | 1/20 | 0.41 |
| ▸ | SKP1 | P63208 | 1/20 | 0.41 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.41 |
| ▸ | NPC1L1 | Q9UHC9 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 2/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8866425 | 0.89 | ACACB (0.42) | ACACBACACACKS1BSKP1SKP2 | |
| SCHEMBL9233214 | 0.89 | NPC1L1 (0.41) | ACACBACACACKS1BSKP1SKP2 | |
| SCHEMBL8866469 | 0.86 | ACACB (0.46) | ACACBACACACKS1BSKP1SKP2 | |
| SCHEMBL8866085 | 0.86 | ACACB (0.54) | ACACBACACACKS1BSKP1SKP2 | |
| SCHEMBL8866088 | 0.81 | ACACB (0.45) | ACACBACACACKS1BSKP1SKP2 | |
| SCHEMBL8866736 | 0.80 | ALDH1A1 (0.41) | ACACBACACATHRBABL1RIN1 | |
| SCHEMBL8866813 | 0.78 | ACACB (0.51) | ACACBACACACKS1BSKP1SKP2 | |
| SCHEMBL9233943 | 0.78 | ACACB (0.41) | ACACBACACACKS1BSKP1SKP2 | |
| SCHEMBL9232532 | 0.76 | ACACB (0.43) | ACACBACACACKS1BSKP1SKP2 | |
| SCHEMBL8867348 | 0.75 | SUV39H2 (0.43) | THRBTP53ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5614531-A | Adhesion receptor antagonists | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1997-03-25 | — | — | US | disclosed |