Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.52 |
| ▸ | CTSC | P53634 | 2/20 | 0.47 |
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 2/20 | 0.41 |
| ▸ | CCR3 | P51677 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9054827 | 0.85 | CNR2 (0.58) | ALDH1A1HTTNCOA1SMN1; SMN2NCOA3 | |
| SCHEMBL6813188 | 0.84 | ALDH1A1 (0.71) | ALDH1A1HTTNCOA1SMN1; SMN2NCOA3 | |
| SCHEMBL16889096 | 0.84 | ALDH1A1 (0.71) | ALDH1A1HTTNCOA1SMN1; SMN2NCOA3 | |
| SCHEMBL8866666 | 0.82 | ALDH1A1 (0.52) | ALDH1A1HTTNCOA1SMN1; SMN2NCOA3 | |
| Hydrochloric Acid SCHEMBL6813768 | 0.82 | ALDH1A1 (0.69) | ALDH1A1HTTNCOA1SMN1; SMN2NCOA3 | |
| SCHEMBL5304987 | 0.81 | ALDH1A1 (0.60) | ALDH1A1HTTNCOA1SMN1; SMN2NCOA3 | |
| Fumaric Acid SCHEMBL8866914 | 0.81 | ALDH1A1 (0.53) | ALDH1A1HTTNCOA1SMN1; SMN2NCOA3 | |
| Maleic Acid SCHEMBL8866899 | 0.81 | ALDH1A1 (0.53) | ALDH1A1HTTNCOA1SMN1; SMN2NCOA3 | |
| SCHEMBL9054159 | 0.80 | ALDH1A1 (0.55) | ALDH1A1HTTNCOA1SMN1; SMN2NCOA3 | |
| SCHEMBL9322630 | 0.78 | ALDH1A1 (0.58) | ALDH1A1HTTNCOA1SMN1; SMN2NCOA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5605916-A | Arylalkyl-amines having anticonvulsant and neuroprotective properties | ASTRA AB (SE) | 1997-02-25 | — | — | US | disclosed |
| US-5539120-A | Arylalkyl-amines having anticonvulsant and neuroprotective properties | AGENCE SPATIALE EUROPEENNE (FR) | 1996-07-23 | — | — | US | disclosed |
| EP-0356035-B1 | Arylkalkyl-amines and -amides having anticonvulsant and neuroprotective properties | ASTRA AB (SE) | 1996-03-13 | — | — | EP | disclosed |
| US-5430044-A | Arylalkyl-amines and -amides having anticonvulsant and neuroprotective properties | FISONS CORPORATION (GB) | 1995-07-04 | — | — | US | disclosed |
| EP-0648489-A1 | Arylalkylamides having neuroprotective properties | FISONS CORPORATION (US) | 1995-04-19 | — | — | EP | disclosed |
| EP-0648745-A1 | Arylalkylamine having anticonvulsant and neuroprotective properties | Astra Aktiebolag (SE) | 1995-04-19 | — | — | EP | disclosed |
| US-5331007-A | Arylalkyl-amines and -amides having anticonvulsant and neuroprotective properties | FISONS CORPORATION (US) | 1994-07-19 | — | — | US | disclosed |
| WO-1991011995-A1 | ARYLALKYL-AMINES AND -AMIDES HAVING ANTICONVULSANT AND NEUROPROTECTIVE PROPERTIES | FISONS CORPORATION (US) | 1991-08-22 | — | — | WO | disclosed |