Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 11/20 | 0.45 |
| ▸ | ACACA | Q13085 | 8/20 | 0.45 |
| ▸ | TTK | P33981 | 5/20 | 0.40 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.38 |
| ▸ | WDR5 | P61964 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8866814 | 0.91 | ACACB (0.49) | ACACBACACAIRAK1WDR5 | |
| SCHEMBL8866088 | 0.87 | ACACB (0.45) | ACACBACACATTKGPR119 | |
| SCHEMBL8866482 | 0.87 | ACACB (0.47) | ACACBACACATTKIRAK1 | |
| SCHEMBL8866508 | 0.87 | ACACB (0.56) | ACACBACACATTKIRAK1 | |
| SCHEMBL8867053 | 0.82 | NPC1 (0.38) | TTKGPR119WDR5 | |
| SCHEMBL8866425 | 0.80 | ACACB (0.42) | ACACBACACAIRAK1 | |
| SCHEMBL9229561 | 0.80 | ACACB (0.41) | ACACBACACATTKIRAK1GPR119 | |
| SCHEMBL8867021 | 0.79 | ACACB (0.50) | ACACBACACAIRAK1WDR5 | |
| SCHEMBL9233943 | 0.79 | ACACB (0.41) | ACACBACACAIRAK1GPR119 | |
| SCHEMBL8866714 | 0.79 | ACACB (0.50) | ACACBACACAIRAK1WDR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5614531-A | Adhesion receptor antagonists | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1997-03-25 | — | — | US | disclosed |