Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 9/20 | 0.41 |
| ▸ | ACACA | Q13085 | 7/20 | 0.41 |
| ▸ | NPC1L1 | Q9UHC9 | 4/20 | 0.39 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.38 |
| ▸ | CKS1B | P61024 | 1/20 | 0.37 |
| ▸ | SKP1 | P63208 | 1/20 | 0.37 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.37 |
| ▸ | SUV39H2 | Q9H5I1 | 1/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9233214 | 0.89 | NPC1L1 (0.41) | ACACBACACANPC1L1IRAK1CKS1B | |
| SCHEMBL8866425 | 0.89 | ACACB (0.42) | ACACBACACANPC1L1IRAK1CKS1B | |
| SCHEMBL8866508 | 0.84 | ACACB (0.56) | ACACBACACAIRAK1CKS1BSKP1 | |
| SCHEMBL8866482 | 0.84 | ACACB (0.47) | ACACBACACAIRAK1CKS1BSKP1 | |
| SCHEMBL9234782 | 0.81 | HPGDS (0.40) | ACACBACACANPC1L1SUV39H2GPR119 | |
| SCHEMBL8867046 | 0.79 | ACACB (0.45) | ACACBACACAIRAK1GPR119 | |
| SCHEMBL8866802 | 0.78 | ACACB (0.42) | ACACBACACANPC1L1CKS1BSKP1 | |
| SCHEMBL8867021 | 0.77 | ACACB (0.50) | ACACBACACAIRAK1CKS1BSKP1 | |
| SCHEMBL9229598 | 0.77 | SUV39H2 (0.42) | SUV39H2GPR119 | |
| Trifluoroacetic Acid SCHEMBL9233271 | 0.74 | HDAC4 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0668278-A1 | Adhesion receptor antagonists | MERCK PATENT GmbH (DE) | 1995-08-23 | — | — | EP | disclosed |