Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | EIF4E | P06730 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | XDH | P47989 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3368389 | 0.85 | RAB9A (0.68) | RAB9AKDM4ESMN1; SMN2POLBNPC1 | |
| SCHEMBL8867718 | 0.79 | RAB9A (1.00) | RAB9AKDM4ESMN1; SMN2POLBNPC1 | |
| SCHEMBL8866822 | 0.78 | RAB9A (0.72) | RAB9AKDM4ESMN1; SMN2POLBNPC1 | |
| SCHEMBL5048868 | 0.77 | SMN1; SMN2 (0.62) | RAB9AKDM4ESMN1; SMN2POLBNPC1 | |
| SCHEMBL3418888 | 0.76 | SMN1; SMN2 (0.65) | RAB9AKDM4ESMN1; SMN2POLBNPC1 | |
| SCHEMBL3413746 | 0.74 | KDM4E (0.65) | RAB9AKDM4ESMN1; SMN2POLBNPC1 | |
| SCHEMBL14109827 | 0.72 | RAB9A (0.60) | RAB9AKDM4ESMN1; SMN2POLBNPC1 | |
| SCHEMBL8868068 | 0.72 | RAB9A (0.65) | RAB9AKDM4ESMN1; SMN2POLBNPC1 | |
| SCHEMBL3436649 | 0.72 | KDM4E (0.55) | RAB9AKDM4ESMN1; SMN2POLBNPC1 | |
| SCHEMBL6771671 | 0.72 | HSD17B10 (0.45) | KDM4ESMN1; SMN2POLBGAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5614520-A | 2-arylthiazole derivatives and pharmaceutical composition thereof | TEIJIN LIMITED (JP) | 1997-03-25 | — | — | US | disclosed |
| EP-0513379-B1 | 2-ARYLTHIAZOLE DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | TEIJIN LTD (JP) | 1996-09-11 | — | — | EP | disclosed |
| EP-0513379-A1 | 2-ARYLTHIAZOLE DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | TEIJIN LIMITED (JP) | 1992-11-19 | — | — | EP | disclosed |