Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.58 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | ADRB2 | P07550 | 4/20 | 0.51 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.51 |
| ▸ | AOC3 | Q16853 | 3/20 | 0.50 |
| ▸ | KDM1A | O60341 | 3/20 | 0.49 |
| ▸ | MAOB | P27338 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7298571 | 1.00 | KDM4E (0.63) | KDM4EL3MBTL1ALDH1A1GRIN1GRIN2A | |
| SCHEMBL20689722 | 0.93 | KDM4E (0.73) | KDM4EL3MBTL1ALDH1A1GRIN1GRIN2A | |
| SCHEMBL7347354 | 0.86 | GRIN1 (0.53) | KDM4EL3MBTL1ALDH1A1GRIN1GRIN2A | |
| SCHEMBL1626455 | 0.85 | KDM4E (0.73) | KDM4EL3MBTL1ALDH1A1SMN1; SMN2ADRB2 | |
| SCHEMBL6320068 | 0.85 | KDM4E (0.73) | KDM4EL3MBTL1ALDH1A1SMN1; SMN2ADRB2 | |
| SCHEMBL7298568 | 0.85 | KDM4E (0.61) | KDM4EL3MBTL1ALDH1A1GRIN1GRIN2A | |
| SCHEMBL27405047 | 0.85 | KDM4E (0.61) | KDM4EL3MBTL1ALDH1A1GRIN1GRIN2A | |
| SCHEMBL25590884 | 0.85 | ALDH1A1 (0.61) | KDM4EL3MBTL1ALDH1A1GRIN1GRIN2A | |
| Anisole SCHEMBL10524597 | 0.84 | KDM4E (0.57) | KDM4EL3MBTL1ALDH1A1SMN1; SMN2ADRB2 | |
| Hydrochloric Acid SCHEMBL30662166 | 0.84 | KDM4E (0.70) | KDM4EL3MBTL1ALDH1A1SMN1; SMN2ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0659190-A1 | ANTINEOPLASTIC HETERONAPHTHOQUINONES | BIOCHEM PHARMA INC (CA) | 1995-06-28 | — | — | EP | claimed |
| WO-1994011382-A1 | ANTINEOPLASTIC HETERONAPHTHOQUINONES | BIOCHEM PHARMA INC. (CA) | 1994-05-26 | — | — | WO | claimed |
| US-5599966-A | SUITABLE FOR TREATMENT OF DISEASES OF RESPIRATORY PASSAGES | BYK NEDERLAND BV (NL) | 1997-02-04 | — | — | US | disclosed |
| EP-0664788-A1 | SUBSTITUTED ETHANOLAMINE ESTERS | Byk Nederland BV (NL) | 1995-08-02 | — | — | EP | disclosed |
| WO-1994008945-A1 | SUBSTITUTED ETHANOLAMINE ESTERS | BYK NEDERLAND BV (NL) | 1994-04-28 | — | — | WO | disclosed |