Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 3/20 | 0.42 |
| ▸ | MAOB | P27338 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | JAK2 | O60674 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8867428 | 1.00 | ALDH1A1 (0.52) | ALDH1A1KMT2ANPC1RAB9AMAPT | |
| SCHEMBL8867056 | 0.87 | KMT2A (0.51) | ALDH1A1KMT2AMAPTGAAMAOA | |
| SCHEMBL8867437 | 0.87 | ALDH1A1 (0.50) | ALDH1A1KMT2ANPC1RAB9AMAPT | |
| SCHEMBL8867062 | 0.87 | KMT2A (0.51) | ALDH1A1KMT2AMAPTGAAMAOA | |
| SCHEMBL8867588 | 0.86 | MAPT (0.53) | ALDH1A1KMT2AMAPTGAASMN1; SMN2 | |
| SCHEMBL8867582 | 0.86 | MAPT (0.53) | ALDH1A1KMT2AMAPTGAASMN1; SMN2 | |
| SCHEMBL8868021 | 0.85 | ALDH1A1 (0.44) | ALDH1A1KMT2AMAPTGAASMN1; SMN2 | |
| SCHEMBL8868024 | 0.85 | ALDH1A1 (0.44) | ALDH1A1KMT2AMAPTGAASMN1; SMN2 | |
| SCHEMBL8867679 | 0.84 | MAOB (0.46) | ALDH1A1KMT2AMAPTMAOAMAOB | |
| SCHEMBL8867682 | 0.84 | MAOB (0.46) | ALDH1A1KMT2AMAPTMAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5686484-A | ANTHELMINTICS, ACARICIDES, INSECTICIDES | SANKYO CO., LTD. (JP) | 1997-11-11 | — | — | US | disclosed |