SCHEMBL8867685

SCHEMBL8867685

CNC(=O)Nc1cccc(/C=C/CO)c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 4/20 0.46
MAOA P21397 3/20 0.46
RHOA P61586 1/20 0.45
PKM P14618 1/20 0.43
MEN1 O00255 1/20 0.42
KMT2A Q03164 1/20 0.42
FGFR3 P22607 1/20 0.42
KDR P35968 1/20 0.42
MMP1 P03956 2/20 0.41
MMP2 P08253 2/20 0.41
MMP9 P14780 2/20 0.41
SAE1 Q9UBE0 1/20 0.41
UBA2 Q9UBT2 1/20 0.41
ANXA2 P07355 1/20 0.41
S100A10 P60903 1/20 0.41
SNCA P37840 2/20 0.40
CYP4F2 P78329 1/20 0.40
CYP4A11 Q02928 1/20 0.40
GLA P06280 1/20 0.40
MAPT P10636 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8867679 0.88 MAOB (0.46) MAOBMAOAPKMMEN1KMT2A
SCHEMBL8867682 0.88 MAOB (0.46) MAOBMAOAPKMMEN1KMT2A
SCHEMBL8867294 0.87 MAOB (0.53) MAOBMAOARHOAPKMMEN1
SCHEMBL8866966 0.86 MAPT (0.46) MAOBMAOARHOAPKMFGFR3
SCHEMBL8868715 0.85 CA12 (0.51) MAOBMAOARHOAMEN1KMT2A
SCHEMBL8868116 0.83 MAPT (0.60) PKMMEN1KMT2AFGFR3KDR
SCHEMBL8867234 0.83 MAOB (0.42) MAOBMAOARHOAPKMMEN1
SCHEMBL8868501 0.83 MEN1 (0.47) MAOBMAOARHOAMEN1KMT2A
SCHEMBL8867748 0.83 FGFR3 (0.45) MAOBMAOARHOAPKMMEN1
SCHEMBL8867437 0.82 ALDH1A1 (0.50) MAOBMAOARHOAMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5686484-A ANTHELMINTICS, ACARICIDES, INSECTICIDES SANKYO CO., LTD. (JP) 1997-11-11 US disclosed