Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 10/20 | 0.68 |
| ▸ | RAB9A | P51151 | 10/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.68 |
| ▸ | HTT | P42858 | 5/20 | 0.68 |
| ▸ | POLB | P06746 | 1/20 | 0.68 |
| ▸ | MAPT | P10636 | 3/20 | 0.64 |
| ▸ | MEN1 | O00255 | 3/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.64 |
| ▸ | PKM | P14618 | 4/20 | 0.59 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.59 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.59 |
| ▸ | RELA | Q04206 | 3/20 | 0.59 |
| ▸ | CA12 | O43570 | 1/20 | 0.58 |
| ▸ | CA1 | P00915 | 1/20 | 0.58 |
| ▸ | CA2 | P00918 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | CA9 | Q16790 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.58 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8867735 | 0.88 | NPC1 (0.68) | NPC1RAB9ASMN1; SMN2HTTPOLB | |
| SCHEMBL8868654 | 0.82 | EPHX1 (0.63) | NPC1RAB9ASMN1; SMN2HTTMAPT | |
| SCHEMBL7923242 | 0.82 | MEN1 (0.67) | NPC1RAB9ASMN1; SMN2HTTPOLB | |
| SCHEMBL5275055 | 0.82 | NPC1 (0.68) | NPC1RAB9ASMN1; SMN2HTTPOLB | |
| SCHEMBL14052828 | 0.82 | HRH3 (0.61) | NPC1RAB9ASMN1; SMN2MAPTMEN1 | |
| SCHEMBL4919470 | 0.81 | RAB9A (1.00) | NPC1RAB9ASMN1; SMN2HTTPOLB | |
| SCHEMBL8868957 | 0.81 | CNR1 (0.59) | NPC1RAB9ASMN1; SMN2HTTPOLB | |
| SCHEMBL21834403 | 0.81 | NPC1 (0.81) | NPC1RAB9ASMN1; SMN2HTTPOLB | |
| SCHEMBL24272328 | 0.80 | RAB9A (0.78) | NPC1RAB9ASMN1; SMN2HTTPOLB | |
| SCHEMBL30851501 | 0.79 | RAB9A (1.00) | NPC1RAB9ASMN1; SMN2HTTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5686484-A | ANTHELMINTICS, ACARICIDES, INSECTICIDES | SANKYO CO., LTD. (JP) | 1997-11-11 | — | — | US | disclosed |