Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 3/20 | 0.42 |
| ▸ | FDPS | P14324 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.30 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.30 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.30 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.30 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.30 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.30 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8531067 | 0.80 | — | — | |
| SCHEMBL2983921 | 0.79 | FOLH1 (0.48) | FOLH1LMNAGRIN2DGRIN3BGRIN1 | |
| SCHEMBL8528026 | 0.74 | FOLH1 (0.40) | FOLH1FDPS | |
| SCHEMBL8529495 | 0.74 | FOLH1 (0.40) | FOLH1 | |
| SCHEMBL11316696 | 0.73 | FOLH1 (0.47) | FOLH1LMNA | |
| SCHEMBL2983912 | 0.72 | FOLH1 (0.45) | FOLH1FDPSLMNAGRIN2DGRIN3B | |
| SCHEMBL8528278 | 0.72 | FOLH1 (0.41) | FOLH1 | |
| SCHEMBL11316704 | 0.72 | FDPS (0.33) | FOLH1FDPS | |
| SCHEMBL15873623 | 0.71 | FOLH1 (0.48) | FOLH1LMNA | |
| SCHEMBL8529284 | 0.70 | FOLH1 (0.37) | FOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5698541-A | DISEASES OF CALCIUM METABOLISM; OSTEOPOROSIS | BOEHRINGER MANNHEIM GMBH (DE) | 1997-12-16 | — | — | US | claimed |
| US-5698541-A | DISEASES OF CALCIUM METABOLISM; OSTEOPOROSIS | BOEHRINGER MANNHEIM GMBH (DE) | 1997-12-16 | — | — | US | disclosed |