Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 3/20 | 0.33 |
| ▸ | THRB | P10828 | 3/20 | 0.33 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 4/20 | 0.31 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | SCD | O00767 | 1/20 | 0.30 |
| ▸ | PPARG | P37231 | 4/20 | 0.30 |
| ▸ | PPARD | Q03181 | 4/20 | 0.30 |
| ▸ | PPARA | Q07869 | 4/20 | 0.30 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.30 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.30 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.30 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.30 |
| ▸ | TLR2 | O60603 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ESR1 | P03372 | 1/20 | 0.30 |
| ▸ | FABP4 | P15090 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6281947 | 0.70 | DNTT (0.33) | TSHRPLA2G2ATP53 | |
| SCHEMBL5645954 | 0.67 | GPR84 (0.36) | TSHRPPARGPPARDPPARAGPR84 | |
| SCHEMBL5646162 | 0.67 | GPR84 (0.36) | TSHRPPARGPPARDPPARAGPR84 | |
| SCHEMBL5648481 | 0.67 | GPR84 (0.36) | TSHRPPARGPPARDPPARAGPR84 | |
| SCHEMBL5643378 | 0.67 | GPR84 (0.36) | TSHRPPARGPPARDPPARAGPR84 | |
| SCHEMBL5644363 | 0.67 | GPR84 (0.36) | TSHRPPARGPPARDPPARAGPR84 | |
| SCHEMBL5648179 | 0.67 | GPR84 (0.36) | TSHRPPARGPPARDPPARAGPR84 | |
| SCHEMBL5644553 | 0.67 | GPR84 (0.36) | TSHRPPARGPPARDPPARAGPR84 | |
| SCHEMBL5644317 | 0.67 | GPR84 (0.36) | TSHRPPARGPPARDPPARAGPR84 | |
| SCHEMBL5646346 | 0.67 | GPR84 (0.36) | TSHRPPARGPPARDPPARAGPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5599966-A | SUITABLE FOR TREATMENT OF DISEASES OF RESPIRATORY PASSAGES | BYK NEDERLAND BV (NL) | 1997-02-04 | — | — | US | disclosed |
| EP-0664788-A1 | SUBSTITUTED ETHANOLAMINE ESTERS | Byk Nederland BV (NL) | 1995-08-02 | — | — | EP | disclosed |
| WO-1994008945-A1 | SUBSTITUTED ETHANOLAMINE ESTERS | BYK NEDERLAND BV (NL) | 1994-04-28 | — | — | WO | disclosed |