Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | CA1 | P00915 | 2/20 | 0.52 |
| ▸ | CA2 | P00918 | 2/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.52 |
| ▸ | BRD4 | O60885 | 1/20 | 0.52 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.52 |
| ▸ | MB | P02144 | 1/20 | 0.52 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.52 |
| ▸ | CA3 | P07451 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11116153 | 0.90 | SMN1; SMN2 (0.59) | POLBAOC3SMN1; SMN2HTTL3MBTL1 | |
| SCHEMBL1902060 | 0.90 | SMN1; SMN2 (0.59) | POLBAOC3SMN1; SMN2HTTL3MBTL1 | |
| SCHEMBL8868289 | 0.89 | SMN1; SMN2 (0.57) | POLBAOC3SMN1; SMN2HTTL3MBTL1 | |
| SCHEMBL6949368 | 0.87 | POLB (0.53) | POLBAOC3SMN1; SMN2HTTL3MBTL1 | |
| SCHEMBL29622962 | 0.86 | AOC3 (0.67) | POLBAOC3SMN1; SMN2HTTL3MBTL1 | |
| SCHEMBL29622963 | 0.86 | AOC3 (0.67) | POLBAOC3SMN1; SMN2HTTL3MBTL1 | |
| SCHEMBL25162168 | 0.86 | POLB (0.51) | POLBAOC3SMN1; SMN2HTTL3MBTL1 | |
| SCHEMBL14645643 | 0.85 | CYP4A11 (0.54) | POLBAOC3SMN1; SMN2HTTL3MBTL1 | |
| SCHEMBL2748237 | 0.85 | POLB (0.73) | POLBSMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL8681807 | 0.85 | SMN1; SMN2 (0.57) | POLBAOC3SMN1; SMN2HTTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5686484-A | ANTHELMINTICS, ACARICIDES, INSECTICIDES | SANKYO CO., LTD. (JP) | 1997-11-11 | — | — | US | disclosed |