SCHEMBL29622962

SCHEMBL29622962

CC(=O)Nc1ccc(CCc2ccc(NC(C)=O)cc2)cc1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AOC3 Q16853 1/20 0.67
SMN1; SMN2 Q16637 4/20 0.64
HTT P42858 1/20 0.64
L3MBTL1 Q9Y468 1/20 0.64
KMT2A Q03164 5/20 0.61
ALDH1A1 P00352 4/20 0.61
MEN1 O00255 4/20 0.61
TSHR P16473 2/20 0.61
MAPT P10636 2/20 0.61
TDP1 Q9NUW8 2/20 0.61
CA12 O43570 1/20 0.61
BRD4 O60885 1/20 0.61
NR1I2 O75469 1/20 0.61
CA1 P00915 1/20 0.61
CA2 P00918 1/20 0.61
MB P02144 1/20 0.61
CYP1A1 P04798 1/20 0.61
CA3 P07451 1/20 0.61
CYP3A4 P08684 1/20 0.61
RARG P13631 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29622963 1.00 AOC3 (0.67) AOC3SMN1; SMN2HTTL3MBTL1KMT2A
SCHEMBL10961901 0.92 PTPN1 (0.70) AOC3SMN1; SMN2HTTL3MBTL1KMT2A
SCHEMBL11116153 0.91 SMN1; SMN2 (0.59) AOC3SMN1; SMN2HTTL3MBTL1KMT2A
SCHEMBL1902060 0.91 SMN1; SMN2 (0.59) AOC3SMN1; SMN2HTTL3MBTL1KMT2A
SCHEMBL8868289 0.90 SMN1; SMN2 (0.57) AOC3SMN1; SMN2HTTL3MBTL1KMT2A
SCHEMBL7211903 0.90 AOC3 (0.61) AOC3SMN1; SMN2HTTL3MBTL1KMT2A
SCHEMBL6629816 0.90 SMN1; SMN2 (0.57) AOC3SMN1; SMN2HTTL3MBTL1KMT2A
SCHEMBL8681807 0.90 SMN1; SMN2 (0.57) AOC3SMN1; SMN2HTTL3MBTL1KMT2A
SCHEMBL9562395 0.89 TSHR (0.81) AOC3SMN1; SMN2HTTL3MBTL1KMT2A
SCHEMBL10750700 0.88 ALDH1A1 (0.57) AOC3SMN1; SMN2HTTL3MBTL1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111303411-B Triphenylimidazole o-hydroxy azo polymer, and preparation method and application thereof 湘潭大学 2022-05-13 CN claimed
CN-111303411-B Triphenylimidazole o-hydroxy azo polymer, and preparation method and application thereof 湘潭大学 2022-05-13 CN disclosed
CN-111303411-B Triphenylimidazole o-hydroxy azo polymer, and preparation method and application thereof 湘潭大学 2022-05-13 CN disclosed