Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Piperazine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL15855950 | 1.00 | HIF1A (0.86) | — | |
| Piperazine SCHEMBL632421 | 1.00 | — | — | |
| Piperazine SCHEMBL5370033 | 0.94 | — | — | |
| Piperazine SCHEMBL5380983 | 0.94 | — | — | |
| Piperazine SCHEMBL27901557 | 0.94 | — | — | |
| Piperazine SCHEMBL10945900 | 0.94 | HIF1A (0.75) | — | |
| Piperazine SCHEMBL5370035 | 0.94 | HIF1A (0.75) | — | |
| Piperazine SCHEMBL28152403 | 0.94 | — | — | |
| SCHEMBL7052601 | 0.93 | HIF1A (1.00) | — | |
| SCHEMBL22003 | 0.93 | HIF1A (1.00) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 86 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118007271-A | Method for preparing high-temperature-resistant high-strength spandex | 华峰重庆氨纶有限公司 | 2024-05-10 | — | — | CN | claimed |
| EP-0503235-B1 | Polyamide and polyesteramide based on trimerised fatty acids-process of production and application for glues | WITCO GMBH (DE) | 1996-09-11 | — | — | EP | claimed |
| EP-0705287-A1 | POLYUREAURETHANE PRIMERLESS STRUCTURAL ADHESIVE | ASHLAND OIL, INC. (US) | 1996-04-10 | — | — | EP | claimed |
| EP-0705287-A4 | POLYUREAURETHANE PRIMERLESS STRUCTURAL ADHESIVE | ASHLAND OIL INC (US) | 1995-06-20 | — | — | EP | claimed |
| WO-1993018074-A1 | POLYUREAURETHANE PRIMERLESS STRUCTURAL ADHESIVE | ASHLAND OIL, INC. (US) | 1993-09-16 | — | — | WO | claimed |
| US-4556509-A | IMPROVES WATER FOAMING AND DEGREASING | COLGATE-PALMOLIVE COMPANY (US) | 1985-12-03 | — | — | US | claimed |
| JP-62244404-A | — | — | None | — | — | JP | disclosed |
| JP-62244403-A | — | — | None | — | — | JP | disclosed |
| CN-118142347-A | Preparation method of aliphatic positive nanofiltration membrane based on polyamine diacid chloride monomer | 中国石油大学(华东) | 2024-06-07 | — | — | CN | disclosed |
| CN-118147094-A | Protein capable of catalyzing monoamidation of symmetrical diamine and derived from fungi and application | 上海交通大学 | 2024-06-07 | — | — | CN | disclosed |
| US-11981827-B2 | Waterborne polyurethane dispersion and method for preparing the same | DOW GLOBAL TECHNOLOGIES LLC (US) | 2024-05-14 | — | — | US | disclosed |
| CN-118007271-A | Method for preparing high-temperature-resistant high-strength spandex | 华峰重庆氨纶有限公司 | 2024-05-10 | — | — | CN | disclosed |
| EP-3935098-B1 | WATERBORNE POLYURETHANE DISPERSION AND METHOD FOR PREPARING THE SAME | DOW GLOBAL TECHNOLOGIES LLC (US) | 2023-11-22 | — | — | EP | disclosed |
| US-5002806-A | Polyol, slow and fast reacting polyamines; fiberglass reinforced polyester substrates | ASHLAND OIL, INC. (US) | 1991-03-26 | — | — | US | disclosed |
| EP-0382236-A2 | Polyamide laminated on thermoplastic polyurethane | THE B.F. GOODRICH COMPANY (US) | 1990-08-16 | — | — | EP | disclosed |
| JP-S62244403-A | PERMSELECTIVE MEMBRANE | TOYOBO CO LTD | 1987-10-24 | — | — | JP | disclosed |
| JP-S62244404-A | PERMSELECTIVE MEMBRANE | TOYOBO CO LTD | 1987-10-24 | — | — | JP | disclosed |
| US-4695383-A | COPOLYAMIDE FROM A DIAMINODIPHENYL SULFONE | TOYO BOSEKI KABUSHIKI KAISHA (JP) | 1987-09-22 | — | — | US | disclosed |
| US-4410686-A | Norbornyl modified polyesteramides and process for preparing same | THE DOW CHEMICAL COMPANY (US) | 1983-10-18 | — | — | US | disclosed |
| US-3956329-A | CRACKING CYCLIZATION | SHUNAN PETROCHEMICAL COMPANY, LTD. (JA) | 1976-05-11 | — | — | US | disclosed |