SCHEMBL22003

SCHEMBL22003

C1CNCCNCCNCCN1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 1/20 1.00
MAPT P10636 1/20 1.00
PDE4A P27815 1/20 1.00
KDR P35968 1/20 1.00
CXCR4 P61073 1/20 0.67
SMN1; SMN2 Q16637 1/20 0.67
ALDH1A1 P00352 1/20 0.50
KDM4E B2RXH2 1/20 0.50
GAA P10253 1/20 0.50
CYP2C9 P11712 1/20 0.50
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4299924 1.00 HIF1A (1.00) HIF1AMAPTPDE4AKDRCXCR4
SCHEMBL577429 1.00 HIF1A (1.00) HIF1AMAPTPDE4AKDRCXCR4
SCHEMBL8199316 1.00 HIF1A (1.00) HIF1AMAPTPDE4AKDRCXCR4
SCHEMBL7052601 1.00 HIF1A (1.00) HIF1AMAPTPDE4AKDRCXCR4
SCHEMBL5033222 1.00 HIF1A (1.00) HIF1AMAPTPDE4AKDRCXCR4
SCHEMBL2373879 1.00 HIF1A (1.00) HIF1AMAPTPDE4AKDRCXCR4
Piperazine SCHEMBL734764 1.00 HIF1A (1.00) HIF1AMAPTPDE4AKDRCXCR4
SCHEMBL3999265 1.00 HIF1A (1.00) HIF1AMAPTPDE4AKDRCXCR4
SCHEMBL576335 1.00 HIF1A (1.00) HIF1AMAPTPDE4AKDRCXCR4
Piperazine SCHEMBL8010246 1.00

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 13704 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122076259-A High-temperature-resistant solvent-resistant polyurea-based organic solvent reverse osmosis membrane and preparation method thereof 2026-05-26 CN claimed
US-20260137821-A1 PEPTIDE STRUCTURE TARGETING CARBONIC DEHYDROGENASE IX AND USE THEREOF C-BIOMEX CO., LTD. (KR) 2026-05-21 US claimed
WO-2026104061-A1 A METHOD FOR THE PREPARATION OF CYCLEN Midas Pharma GmbH (DE) 2026-05-21 WO claimed
EP-4211146-B1 SYNTHETIC CYCLIC PEPTIDE MIMETICS UNIV BAR ILAN (IL) 2026-05-20 EP claimed
CN-121045338-B Cyclic peptide targeting CAIX and preparation method and application thereof 原子高科股份有限公司 2026-05-19 CN claimed
US-12629343-B2 Multi-layer transdermal drug delivery system containing ibuprofen or structural analogue thereof Demotech, Inc. (CN) 2026-05-19 US claimed
CN-122070148-A Inhibitors of targeted fibroblast activation proteins 苏州博锐创合医药有限公司 2026-05-19 CN claimed
WO-2026098441-A1 COMPOSITION AND METHOD FOR CANCER TREATMENT USING POLYPEPTIDE CONJUGATES SUZHOU SMARTNUCLIDE BIOPHARMACEUTICAL CO., LTD. (CN) 2026-05-15 WO claimed
EP-4739689-A1 NOVEL BISPIDINE-BASED METAL CHELATING LIGANDS DISPLAYING GOOD RELAXIVITY Université de Strasbourg (FR) 2026-05-13 EP claimed
EP-3986465-B1 SITE-SPECIFIC, KINETICALLY INERT CONJUGATION OF LABELS AND/OR CARRIERS TO TARGET MOLECULES SUCH AS HIS-TAGGED PROTEINS VIA METAL COMPLEX REAGENTS MAX PLANCK GESELLSCHAFT (DE) 2026-05-13 EP claimed
EP-0048678-B1 COMPOSITE OF RUBBER AND METAL REINFORCEMENT THEREFORE THE GOODYEAR TIRE & RUBBER COMPANY (US) 1985-06-12 EP claimed
US-4521558-A ALLYL PHOSPHATE OR PHOSPHITE ESTERS THE GOODYEAR TIRE & RUBBER COMPANY (US) 1985-06-04 US claimed
EP-0113582-A2 Macrocyclic polyamine and polycyclic polyamine multifunctional lubricating oil additives EXXON RESEARCH AND ENGINEERING COMPANY (US) 1984-07-18 EP claimed
US-4391318-A CONTAINS CYANURIC DERIVATIVE, FOR TIRES, BELTS AND HOSES THE GOODYEAR TIRE & RUBBER COMPANY (US) 1983-07-05 US claimed
EP-0073174-A1 Composite of rubber and metal reinforcement therefor THE GOODYEAR TIRE & RUBBER COMPANY (US) 1983-03-02 EP claimed
EP-0065477-A1 Composite of rubber and metal reinforcement therefor THE GOODYEAR TIRE & RUBBER COMPANY (US) 1982-11-24 EP claimed
EP-0065476-A1 Composite of rubber and metal reinforcement therefor THE GOODYEAR TIRE & RUBBER COMPANY (US) 1982-11-24 EP claimed
EP-0048678-A2 Composite of rubber and metal reinforcement therefore THE GOODYEAR TIRE & RUBBER COMPANY (US) 1982-03-31 EP claimed
EP-0018894-B1 ESTERS OF ALLETHROLONE DERIVATIVES AND CARBOXYLIC ACIDS, PROCESS FOR THEIR PREPARATION AND THE COMPOSITIONS CONTAINING THEM ROUSSEL-UCLAF (FR) 1982-02-17 EP claimed
US-3930867-A MACROCYCLIC POLYAMINES AS SENSITIZERS FOR SILVER HALIDE EMULSIONS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1976-01-06 US claimed