Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P4HTM | Q9NXG6 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | NAAA | Q02083 | 1/20 | 0.41 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | FBP1 | P09467 | 9/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.39 |
| ▸ | STAMBP | O95630 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8869570 | 0.96 | SMN1; SMN2 (0.46) | P4HTMSMN1; SMN2HDAC6BCL2L1MCL1 | |
| SCHEMBL8869621 | 0.91 | P4HTM (0.45) | P4HTMSMN1; SMN2CA2HDAC6NAAA | |
| SCHEMBL8868684 | 0.90 | P4HTM (0.47) | P4HTMSMN1; SMN2CA2NAAABCL2L1 | |
| SCHEMBL8868794 | 0.90 | CA2 (0.50) | P4HTMSMN1; SMN2CA2NAAAKMT2A | |
| SCHEMBL8868275 | 0.90 | HPGD (0.42) | P4HTMSMN1; SMN2FBP1KMT2AGAA | |
| SCHEMBL9140170 | 0.89 | P4HTM (0.47) | P4HTMSMN1; SMN2CA2HDAC6NAAA | |
| SCHEMBL8868137 | 0.89 | P4HTM (0.47) | P4HTMKMT2ASTAMBPMAPT | |
| SCHEMBL8868272 | 0.89 | P4HTM (0.48) | P4HTMSMN1; SMN2BCL2L1MCL1KMT2A | |
| SCHEMBL8868850 | 0.89 | P4HTM (0.46) | P4HTMSMN1; SMN2HDAC6MAPT | |
| SCHEMBL8868702 | 0.88 | P4HTM (0.47) | P4HTMSMN1; SMN2HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5607954-A | Sulfonamido- and sulfonamidocarbonylpyridine-2-carboxamides and their pyridine-n-oxides, process for their preparation and their use as pharmaceuticals | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-03-04 | — | — | US | disclosed |