Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P4HTM | Q9NXG6 | 7/20 | 0.76 |
| ▸ | EGLN1 | Q9GZT9 | 4/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | USP5 | P45974 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | HPGDS | O60760 | 1/20 | 0.43 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.43 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8868206 | 0.88 | P4HTM (0.59) | P4HTMEGLN1NPC1RAB9AKDM4E | |
| SCHEMBL8867919 | 0.88 | P4HTM (0.76) | P4HTMNPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL8869957 | 0.87 | P4HTM (0.67) | P4HTMRAB9AALDH1A1L3MBTL1PTPN1 | |
| SCHEMBL8867592 | 0.86 | P4HTM (0.57) | P4HTMEGLN1NPC1RAB9AKDM4E | |
| SCHEMBL9018455 | 0.86 | P4HTM (1.00) | P4HTMNPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL8869639 | 0.86 | P4HTM (0.62) | P4HTMEGLN1NPC1RAB9AKDM4E | |
| SCHEMBL8869591 | 0.85 | P4HTM (0.56) | P4HTMEGLN1NPC1RAB9AKDM4E | |
| SCHEMBL8869402 | 0.85 | P4HTM (0.64) | P4HTMEGLN1NPC1RAB9AKDM4E | |
| SCHEMBL8869393 | 0.84 | P4HTM (0.63) | P4HTMNPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL8869186 | 0.84 | P4HTM (0.69) | P4HTMNPC1RAB9AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5607954-A | Sulfonamido- and sulfonamidocarbonylpyridine-2-carboxamides and their pyridine-n-oxides, process for their preparation and their use as pharmaceuticals | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-03-04 | — | — | US | disclosed |