Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P4HTM | Q9NXG6 | 6/20 | 0.69 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MTOR | P42345 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | AHR | P35869 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.42 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.42 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.42 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.42 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.42 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.42 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.42 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8868785 | 0.89 | P4HTM (0.55) | P4HTMHPGDALDH1A1NPC1RAB9A | |
| SCHEMBL8867919 | 0.89 | P4HTM (0.76) | P4HTMALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8867612 | 0.88 | P4HTM (0.53) | P4HTMHPGDALDH1A1NPC1RAB9A | |
| SCHEMBL8868663 | 0.87 | P4HTM (0.52) | P4HTMHPGDALDH1A1NPC1RAB9A | |
| SCHEMBL8869678 | 0.87 | P4HTM (0.52) | P4HTMHPGDALDH1A1NPC1RAB9A | |
| SCHEMBL9018572 | 0.85 | P4HTM (0.77) | P4HTMHPGDALDH1A1NPC1RAB9A | |
| SCHEMBL8868915 | 0.84 | P4HTM (0.66) | P4HTMHPGDALDH1A1 | |
| SCHEMBL7862679 | 0.84 | P4HTM (0.56) | P4HTMHPGDNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8869322 | 0.84 | P4HTM (0.76) | P4HTMALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8869393 | 0.83 | P4HTM (0.63) | P4HTMALDH1A1NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5607954-A | Sulfonamido- and sulfonamidocarbonylpyridine-2-carboxamides and their pyridine-n-oxides, process for their preparation and their use as pharmaceuticals | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-03-04 | — | — | US | disclosed |