Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P4HTM | Q9NXG6 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.50 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.50 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.49 |
| ▸ | METAP2 | P50579 | 1/20 | 0.49 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.49 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8868187 | 0.85 | POLB (0.55) | MEN1KMT2APOLBCA1CA2 | |
| SCHEMBL8868644 | 0.81 | HTT (0.53) | MEN1KMT2APOLBCA1CA2 | |
| SCHEMBL9142918 | 0.80 | POLB (0.50) | MEN1KMT2APOLBCA1CA2 | |
| SCHEMBL9574751 | 0.79 | MEN1 (0.51) | MEN1KMT2APOLBCA1CA2 | |
| SCHEMBL25073308 | 0.79 | P4HTM (0.49) | P4HTMMEN1KMT2APOLBALDH1A1 | |
| SCHEMBL9142910 | 0.79 | FFAR1 (0.48) | MEN1KMT2APOLBCA1CA2 | |
| SCHEMBL1028840 | 0.78 | CA1 (0.71) | MEN1KMT2APOLBCA1CA2 | |
| SCHEMBL16598076 | 0.78 | P4HTM (0.58) | P4HTMMEN1KMT2APOLBCA1 | |
| SCHEMBL8869163 | 0.78 | POLB (0.47) | MEN1KMT2APOLBBDKRB1HSD17B3 | |
| SCHEMBL8868652 | 0.78 | PKM (0.50) | MEN1KMT2APOLBBDKRB1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5607954-A | Sulfonamido- and sulfonamidocarbonylpyridine-2-carboxamides and their pyridine-n-oxides, process for their preparation and their use as pharmaceuticals | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-03-04 | — | — | US | disclosed |
| CN-1089603-A | New pyridine-2-carboxylicesters and pyridine-N-oxide, method for making and medicinal | HOECHST AG (DE) | 1994-07-20 | — | — | CN | disclosed |
| EP-0562512-A1 | Sulfonamido- and sulfonamidocarbonyl-pyridine-2-carboxamides and their pyridine-N-oxides, process for their preparation and their use as medicines | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-09-29 | — | — | EP | disclosed |