Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | CA7 | P43166 | 1/20 | 0.52 |
| ▸ | CA9 | Q16790 | 1/20 | 0.52 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8868897 | 0.94 | ALDH1A1 (0.56) | ALDH1A1SMN1; SMN2LMNAMAPK1MAPT | |
| SCHEMBL9139641 | 0.92 | ALDH1A1 (0.56) | ALDH1A1SMN1; SMN2LMNAMAPK1MAPT | |
| SCHEMBL8868339 | 0.91 | CA1 (0.61) | ALDH1A1SMN1; SMN2LMNAMAPK1MAPT | |
| SCHEMBL8867838 | 0.90 | KMT2A (0.56) | ALDH1A1SMN1; SMN2LMNAMAPTHTT | |
| SCHEMBL8868857 | 0.90 | TSHR (0.61) | ALDH1A1SMN1; SMN2LMNAMAPK1MAPT | |
| SCHEMBL7870454 | 0.90 | ALDH1A1 (0.51) | ALDH1A1SMN1; SMN2LMNAMAPK1MAPT | |
| SCHEMBL8869612 | 0.87 | MEN1 (0.49) | ALDH1A1SMN1; SMN2LMNAMAPTRAB9A | |
| SCHEMBL8869195 | 0.86 | MAPT (0.50) | ALDH1A1SMN1; SMN2MAPTGAANPC1 | |
| SCHEMBL9018568 | 0.86 | ALDH1A1 (0.54) | ALDH1A1SMN1; SMN2LMNAMAPK1MAPT | |
| SCHEMBL8869014 | 0.86 | P4HTM (0.54) | ALDH1A1SMN1; SMN2HTTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5607954-A | Sulfonamido- and sulfonamidocarbonylpyridine-2-carboxamides and their pyridine-n-oxides, process for their preparation and their use as pharmaceuticals | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-03-04 | — | — | US | disclosed |